diff --git a/app/code/Magento/InventoryCatalog/Plugin/InventoryApi/StockRepository/PreventDeleting/AssignedToSalesChannelsStockPlugin.php b/app/code/Magento/InventoryCatalog/Plugin/InventoryApi/StockRepository/PreventDeleting/AssignedToSalesChannelsStockPlugin.php
new file mode 100644
index 000000000000..3105844520f0
--- /dev/null
+++ b/app/code/Magento/InventoryCatalog/Plugin/InventoryApi/StockRepository/PreventDeleting/AssignedToSalesChannelsStockPlugin.php
@@ -0,0 +1,49 @@
+<?php
+/**
+ * Copyright © Magento, Inc. All rights reserved.
+ * See COPYING.txt for license details.
+ */
+declare(strict_types=1);
+
+namespace Magento\InventoryCatalog\Plugin\InventoryApi\StockRepository\PreventDeleting;
+
+use Magento\Framework\Exception\CouldNotDeleteException;
+use Magento\InventoryApi\Api\StockRepositoryInterface;
+use Magento\InventorySales\Model\GetAssignedSalesChannelsForStockInterface;
+
+/**
+ * Prevent deleting of Stock which assigned at least one Sales Channel
+ */
+class AssignedToSalesChannelsStockPlugin
+{
+    /**
+     * @var GetAssignedSalesChannelsForStockInterface
+     */
+    private $assignedSalesChannelsForStock;
+
+    /**
+     * @param GetAssignedSalesChannelsForStockInterface $assignedSalesChannelsForStock
+     */
+    public function __construct(
+        GetAssignedSalesChannelsForStockInterface $assignedSalesChannelsForStock
+    ) {
+        $this->assignedSalesChannelsForStock = $assignedSalesChannelsForStock;
+    }
+
+    /**
+     * Prevent deleting of Stock which assigned at least one Sales Channel
+     *
+     * @param StockRepositoryInterface $subject
+     * @param int $stockId
+     * @return void
+     * @throws CouldNotDeleteException
+     * @SuppressWarnings(PHPMD.UnusedFormalParameter)
+     */
+    public function beforeDeleteById(StockRepositoryInterface $subject, int $stockId)
+    {
+        $assignSalesChannels = $this->assignedSalesChannelsForStock->execute($stockId);
+        if (count($assignSalesChannels)) {
+            throw new CouldNotDeleteException(__('Stock has at least one sale channel and could not be deleted.'));
+        }
+    }
+}
diff --git a/app/code/Magento/InventoryCatalog/Plugin/Model/StockRepositoryPlugin.php b/app/code/Magento/InventoryCatalog/Plugin/InventoryApi/StockRepository/PreventDeleting/DefaultStockPlugin.php
similarity index 75%
rename from app/code/Magento/InventoryCatalog/Plugin/Model/StockRepositoryPlugin.php
rename to app/code/Magento/InventoryCatalog/Plugin/InventoryApi/StockRepository/PreventDeleting/DefaultStockPlugin.php
index a44f014c80e3..a4852c5c8d94 100644
--- a/app/code/Magento/InventoryCatalog/Plugin/Model/StockRepositoryPlugin.php
+++ b/app/code/Magento/InventoryCatalog/Plugin/InventoryApi/StockRepository/PreventDeleting/DefaultStockPlugin.php
@@ -3,17 +3,18 @@
  * Copyright © Magento, Inc. All rights reserved.
  * See COPYING.txt for license details.
  */
+declare(strict_types=1);
 
-namespace Magento\InventoryCatalog\Plugin\Model;
+namespace Magento\InventoryCatalog\Plugin\InventoryApi\StockRepository\PreventDeleting;
 
 use Magento\Framework\Exception\CouldNotDeleteException;
 use Magento\InventoryApi\Api\StockRepositoryInterface;
 use Magento\InventoryCatalog\Api\DefaultStockProviderInterface;
 
 /**
- * Class provide Before Plugin on StockRepositoryInterface::deleteByItem to prevent default stock could be deleted
+ * Prevent deleting of Default Stock
  */
-class StockRepositoryPlugin
+class DefaultStockPlugin
 {
     /**
      * @var DefaultStockProviderInterface
@@ -23,17 +24,17 @@ class StockRepositoryPlugin
     /**
      * @param DefaultStockProviderInterface $defaultStockProvider
      */
-    public function __construct(DefaultStockProviderInterface $defaultStockProvider)
-    {
+    public function __construct(
+        DefaultStockProviderInterface $defaultStockProvider
+    ) {
         $this->defaultStockProvider = $defaultStockProvider;
     }
 
     /**
-     * Prevent default source to be deleted
+     * Prevent deleting of Default Stock
      *
      * @param StockRepositoryInterface $subject
      * @param int $stockId
-     *
      * @return void
      * @throws CouldNotDeleteException
      * @SuppressWarnings(PHPMD.UnusedFormalParameter)
diff --git a/app/code/Magento/InventoryCatalog/Test/Api/StockRepository/PreventAssignedToSalesChannelsStockDeletingTest.php b/app/code/Magento/InventoryCatalog/Test/Api/StockRepository/PreventAssignedToSalesChannelsStockDeletingTest.php
new file mode 100644
index 000000000000..331285ff9f10
--- /dev/null
+++ b/app/code/Magento/InventoryCatalog/Test/Api/StockRepository/PreventAssignedToSalesChannelsStockDeletingTest.php
@@ -0,0 +1,52 @@
+<?php
+/**
+ * Copyright © Magento, Inc. All rights reserved.
+ * See COPYING.txt for license details.
+ */
+declare(strict_types=1);
+
+namespace Magento\InventoryCatalog\Test\Api\StockRepository;
+
+use Magento\Framework\Webapi\Exception;
+use Magento\Framework\Webapi\Rest\Request;
+use Magento\TestFramework\TestCase\WebapiAbstract;
+
+class PreventAssignedToSalesChannelsStockDeletingTest extends WebapiAbstract
+{
+    /**
+     * @magentoApiDataFixture ../../../../app/code/Magento/InventorySalesApi/Test/_files/stock_with_sales_channels.php
+     * @throws \Exception
+     */
+    public function testCouldNotDeleteException()
+    {
+        $stockId = 10;
+        $serviceInfo = [
+            'rest' => [
+                'resourcePath' => '/V1/inventory/stock/' . $stockId,
+                'httpMethod' => Request::HTTP_METHOD_DELETE,
+            ],
+            'soap' => [
+                'service' => 'inventoryApiStockRepositoryV1',
+                'operation' => 'inventoryApiStockRepositoryV1DeleteById',
+            ],
+        ];
+        $expectedMessage = 'Stock has at least one sale channel and could not be deleted.';
+        try {
+            (TESTS_WEB_API_ADAPTER == self::ADAPTER_REST)
+                ? $this->_webApiCall($serviceInfo)
+                : $this->_webApiCall($serviceInfo, ['stockId' => $stockId]);
+            $this->fail('Expected throwing exception');
+        } catch (\Exception $e) {
+            if (TESTS_WEB_API_ADAPTER == self::ADAPTER_REST) {
+                $errorData = $this->processRestExceptionResult($e);
+                self::assertEquals($expectedMessage, $errorData['message']);
+                self::assertEquals(Exception::HTTP_BAD_REQUEST, $e->getCode());
+            } elseif (TESTS_WEB_API_ADAPTER == self::ADAPTER_SOAP) {
+                $this->assertInstanceOf('SoapFault', $e);
+                $this->checkSoapFault($e, $expectedMessage, 'env:Sender');
+            } else {
+                throw $e;
+            }
+        }
+    }
+}
diff --git a/app/code/Magento/InventoryCatalog/Test/Api/StockRepository/CouldNotDeleteDefaultStockExceptionTest.php b/app/code/Magento/InventoryCatalog/Test/Api/StockRepository/PreventDefaultStockDeletingTest.php
similarity index 92%
rename from app/code/Magento/InventoryCatalog/Test/Api/StockRepository/CouldNotDeleteDefaultStockExceptionTest.php
rename to app/code/Magento/InventoryCatalog/Test/Api/StockRepository/PreventDefaultStockDeletingTest.php
index 0e2a002f53ca..d17b73a05bc2 100644
--- a/app/code/Magento/InventoryCatalog/Test/Api/StockRepository/CouldNotDeleteDefaultStockExceptionTest.php
+++ b/app/code/Magento/InventoryCatalog/Test/Api/StockRepository/PreventDefaultStockDeletingTest.php
@@ -3,6 +3,7 @@
  * Copyright © Magento, Inc. All rights reserved.
  * See COPYING.txt for license details.
  */
+declare(strict_types=1);
 
 namespace Magento\InventoryCatalog\Test\Api\StockRepository;
 
@@ -12,10 +13,7 @@
 use Magento\TestFramework\Helper\Bootstrap;
 use Magento\InventoryCatalog\Api\DefaultStockProviderInterface;
 
-/**
- * Class CouldNotDeleteDefaultStockExceptionTest
- */
-class CouldNotDeleteDefaultStockExceptionTest extends WebapiAbstract
+class PreventDefaultStockDeletingTest extends WebapiAbstract
 {
     /**
      * @var DefaultStockProviderInterface
@@ -32,8 +30,6 @@ protected function setUp()
     }
 
     /**
-     * Test that default Stock could not be deleted
-     *
      * @throws \Exception
      */
     public function testCouldNotDeleteException()
diff --git a/app/code/Magento/InventoryCatalog/Ui/Component/Control/Stock/DeleteButton.php b/app/code/Magento/InventoryCatalog/Ui/Component/Control/Stock/DeleteButton.php
index 7b8e2546bcec..f9e20031d3b8 100644
--- a/app/code/Magento/InventoryCatalog/Ui/Component/Control/Stock/DeleteButton.php
+++ b/app/code/Magento/InventoryCatalog/Ui/Component/Control/Stock/DeleteButton.php
@@ -3,6 +3,7 @@
  * Copyright © Magento, Inc. All rights reserved.
  * See COPYING.txt for license details.
  */
+declare(strict_types=1);
 
 namespace Magento\InventoryCatalog\Ui\Component\Control\Stock;
 
@@ -11,10 +12,11 @@
 use Magento\InventoryApi\Api\Data\StockInterface;
 use Magento\InventoryCatalog\Api\DefaultStockProviderInterface;
 use Magento\Framework\App\RequestInterface;
+use Magento\InventorySales\Model\GetAssignedSalesChannelsForStockInterface;
 
 /**
  * Represents delete button with pre-configured options
- * Provide an ability to show delete button only when stock id is not default
+ * Provide an ability to show delete button only when stock id is not default or doesn't have assigned sales channels
  */
 class DeleteButton implements ButtonProviderInterface
 {
@@ -28,6 +30,11 @@ class DeleteButton implements ButtonProviderInterface
      */
     private $defaultStockProvider;
 
+    /**
+     * @var GetAssignedSalesChannelsForStockInterface
+     */
+    private $assignedSalesChannelsForStock;
+
     /**
      * @var RequestInterface
      */
@@ -36,15 +43,18 @@ class DeleteButton implements ButtonProviderInterface
     /**
      * @param StockDeleteButton $deleteButton
      * @param DefaultStockProviderInterface $defaultStockProvider
+     * @param GetAssignedSalesChannelsForStockInterface $assignedSalesChannelsForStock
      * @param RequestInterface $request
      */
     public function __construct(
         StockDeleteButton $deleteButton,
         DefaultStockProviderInterface $defaultStockProvider,
+        GetAssignedSalesChannelsForStockInterface $assignedSalesChannelsForStock,
         RequestInterface $request
     ) {
         $this->deleteButton = $deleteButton;
         $this->defaultStockProvider = $defaultStockProvider;
+        $this->assignedSalesChannelsForStock = $assignedSalesChannelsForStock;
         $this->request = $request;
     }
 
@@ -53,7 +63,9 @@ public function __construct(
      */
     public function getButtonData()
     {
-        if ((int)$this->request->getParam(StockInterface::STOCK_ID) === $this->defaultStockProvider->getId()) {
+        $stockId = (int)$this->request->getParam(StockInterface::STOCK_ID);
+        $assignSalesChannels = $this->assignedSalesChannelsForStock->execute($stockId);
+        if ($stockId === $this->defaultStockProvider->getId() || count($assignSalesChannels)) {
             return [];
         }
 
diff --git a/app/code/Magento/InventoryCatalog/etc/di.xml b/app/code/Magento/InventoryCatalog/etc/di.xml
index 997bbe26b3c4..d7e40373206c 100644
--- a/app/code/Magento/InventoryCatalog/etc/di.xml
+++ b/app/code/Magento/InventoryCatalog/etc/di.xml
@@ -9,6 +9,9 @@
     <preference for="Magento\InventoryCatalog\Api\DefaultStockProviderInterface" type="Magento\InventoryCatalog\Model\DefaultStockProvider"/>
     <preference for="Magento\InventoryCatalog\Api\DefaultSourceProviderInterface" type="Magento\InventoryCatalog\Model\DefaultSourceProvider"/>
     <type name="Magento\InventoryApi\Api\StockRepositoryInterface">
-        <plugin name="prevent_default_stock_deletion" type="Magento\InventoryCatalog\Plugin\Model\StockRepositoryPlugin" sortOrder="1"/>
+        <plugin name="prevent_default_stock_deleting"
+                type="Magento\InventoryCatalog\Plugin\InventoryApi\StockRepository\PreventDeleting\DefaultStockPlugin"/>
+        <plugin name="prevent_assigned_to_sales_channels_stock_deleting"
+                type="Magento\InventoryCatalog\Plugin\InventoryApi\StockRepository\PreventDeleting\AssignedToSalesChannelsStockPlugin"/>
     </type>
 </config>
diff --git a/app/code/Magento/InventorySalesApi/Test/_files/stock_with_sales_channels_rollback.php b/app/code/Magento/InventorySalesApi/Test/_files/stock_with_sales_channels_rollback.php
index de50c82457f7..aa40d2e6d91e 100644
--- a/app/code/Magento/InventorySalesApi/Test/_files/stock_with_sales_channels_rollback.php
+++ b/app/code/Magento/InventorySalesApi/Test/_files/stock_with_sales_channels_rollback.php
@@ -8,4 +8,10 @@
 
 /** @var StockRepositoryInterface $stockRepository */
 $stockRepository = Bootstrap::getObjectManager()->get(StockRepositoryInterface::class);
+
+// Firstly clear relations with sales channels
+$stock = $stockRepository->get(10);
+$stock->getExtensionAttributes()->setSalesChannels([]);
+$stockRepository->save($stock);
+
 $stockRepository->deleteById(10);
diff --git a/dev/tests/integration/phpunit.xml.dist b/dev/tests/integration/phpunit.xml.dist
index cca9c1e81f2c..6a7a70fe2cf7 100644
--- a/dev/tests/integration/phpunit.xml.dist
+++ b/dev/tests/integration/phpunit.xml.dist
@@ -54,7 +54,7 @@
         <!-- Semicolon-separated 'glob' patterns, that match global XML configuration files -->
         <const name="TESTS_GLOBAL_CONFIG_DIR" value="../../../app/etc"/>
         <!-- Whether to cleanup the application before running tests or not -->
-        <const name="TESTS_CLEANUP" value="0"/>
+        <const name="TESTS_CLEANUP" value="enabled"/>
         <!-- Memory usage and estimated leaks thresholds -->
         <!--<const name="TESTS_MEM_USAGE_LIMIT" value="1024M"/>-->
         <const name="TESTS_MEM_LEAK_LIMIT" value=""/>