diff --git a/CHANGELOG.md b/CHANGELOG.md
index e108f1d8..ce98805d 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,3 +1,7 @@
+0.6.1 (2023-09-13)
+------------------
+* Feature: GridFS document storage in Mongo-backed instances is now sharded if the mongo server supports it. 
+
 0.6.0 (2023-09-01)
 ------------------
 * Feature: Reports are now grouped by their containing folder on the main UI.
diff --git a/notebooker/serialization/mongo.py b/notebooker/serialization/mongo.py
index 13804e65..f81f90e3 100644
--- a/notebooker/serialization/mongo.py
+++ b/notebooker/serialization/mongo.py
@@ -86,14 +86,22 @@ def load_files_from_gridfs(result_data_store: gridfs.GridFS, result: Dict, do_re
 
 
 class MongoResultSerializer(ABC):
+    instance = None
+
+    def __new__(cls, *args, **kwargs):
+        if not isinstance(cls.instance, cls):
+            cls.instance = object.__new__(cls)
+        return cls.instance
+
     # This class is the interface between Mongo and the rest of the application
     def __init__(self, database_name="notebooker", mongo_host="localhost", result_collection_name="NOTEBOOK_OUTPUT"):
         self.database_name = database_name
         self.mongo_host = mongo_host
         self.result_collection_name = result_collection_name
-        mongo_connection = self.get_mongo_database()
-        self.library = mongo_connection[result_collection_name]
-        self.result_data_store = gridfs.GridFS(mongo_connection, "notebook_data")
+
+        mongo_database = self.get_mongo_database()
+        self.library = mongo_database[result_collection_name]
+        self.result_data_store = gridfs.GridFS(mongo_database, "notebook_data")
 
     def __init_subclass__(cls, cli_options: click.Command = None, **kwargs):
         if cli_options is None:
@@ -104,6 +112,16 @@ def __init_subclass__(cls, cli_options: click.Command = None, **kwargs):
         cls.cli_options = cli_options
         super().__init_subclass__(**kwargs)
 
+    def enable_sharding(self):
+        conn = self.get_mongo_connection()
+        try:
+            conn.admin.command("enableSharding", self.database_name)
+            conn.admin.command({"shardCollection": f"{self.database_name}.notebook_data.chunks",
+                                "key": {"files_id": 1, "n": 1}})
+            logger.info(f"Successfully sharded GridFS collection for {self.database_name}")
+        except pymongo.errors.OperationFailure:
+            logger.error(f"Could not shard {self.database_name}. Continuing.")
+
     def serializer_args_to_cmdline_args(self) -> List[str]:
         args = []
         for cli_arg in self.cli_options.params:
diff --git a/notebooker/web/app.py b/notebooker/web/app.py
index 6d042c47..c7aaeb7d 100644
--- a/notebooker/web/app.py
+++ b/notebooker/web/app.py
@@ -138,6 +138,11 @@ def main(web_config: WebappConfig):
     GLOBAL_CONFIG = web_config
     flask_app = create_app(web_config)
     flask_app = setup_app(flask_app, web_config)
+    serializer = get_serializer_from_cls(web_config.SERIALIZER_CLS, **web_config.SERIALIZER_CONFIG)
+    try:
+        serializer.enable_sharding()
+    except AttributeError:
+        pass
     start_app(web_config)
     logger.info("Notebooker is now running at http://0.0.0.0:%d", web_config.PORT)
     http_server = WSGIServer(("0.0.0.0", web_config.PORT), flask_app)
diff --git a/tests/unit/serialization/test_mongoose.py b/tests/unit/serialization/test_mongoose.py
index 7617ba39..201be808 100644
--- a/tests/unit/serialization/test_mongoose.py
+++ b/tests/unit/serialization/test_mongoose.py
@@ -21,7 +21,8 @@ def test_mongo_filter_status():
 @patch("notebooker.serialization.mongo.gridfs")
 @patch("notebooker.serialization.mongo.MongoResultSerializer.get_mongo_database")
 @patch("notebooker.serialization.mongo.MongoResultSerializer._get_all_job_ids")
-def test_get_latest_job_id_for_name_and_params(_get_all_job_ids, conn, gridfs):
+@patch("notebooker.serialization.mongo.MongoResultSerializer.get_mongo_connection")
+def test_get_latest_job_id_for_name_and_params(conn, _get_all_job_ids, db, gridfs):
     serializer = MongoResultSerializer()
     serializer.get_latest_job_id_for_name_and_params("report_name", None)
     _get_all_job_ids.assert_called_once_with("report_name", None, as_of=None, limit=1)
@@ -29,7 +30,8 @@ def test_get_latest_job_id_for_name_and_params(_get_all_job_ids, conn, gridfs):
 
 @patch("notebooker.serialization.mongo.gridfs")
 @patch("notebooker.serialization.mongo.MongoResultSerializer.get_mongo_database")
-def test__get_all_job_ids(conn, gridfs):
+@patch("notebooker.serialization.mongo.MongoResultSerializer.get_mongo_connection")
+def test__get_all_job_ids(conn, db, gridfs):
     serializer = MongoResultSerializer()
     serializer._get_all_job_ids("report_name", None, limit=1)
     serializer.library.aggregate.assert_called_once_with(