ps4300: $ python -c "import mapnik;mapnik.Projection('+init=epsg:4326')"
[2:46pm] ps4300: Traceback (most recent call last):
[2:46pm] ps4300: File "<string>", line 1, in <module>
[2:46pm] ps4300: RuntimeError: unidentifiable C++ exception
hit using Mapnik 2.1 installer. This is likely a problem with the build - in that boost_python needs to be rebuilt for 10.8 (and the 10.7 binary is invalid) But it needs a closer look.