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README.rst

PPTC PDX Mutational Signatures

Authors: Jo Lynne Rokita
Nathan Kendsersky
Contact: Jo Lynne Rokita (rokita@email.chop.edu)
Organization: CHOP
Status: In-process
Date: 2019-07-15

Introduction

This repo contains code for:

  1. Creation of mutational signature weight matrices
  2. Code for Figure 4G

Details

  • deconstructsigs.sh -- Run first to pull relevant files from figshare
  • theme.R -- Code for Figure 4G ggplot2 theme
  • deconstructsigs-30-finalpub.R -- Code to calculate cosine similarity value for each model and to plot Figure 4G
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