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Fusion pipeline and figures
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README.rst

PPTC PDX Fusion Pipeline

Authors: Komal S. Rathi
Contact: Komal S. Rathi (rathik@email.chop.edu)
Organization: CHOP
Status: Completed
Date: 2019-07-18

Introduction

This repo contains code for:

  1. Fusion detection and filtering
  2. Create publication quality figures.

Details

  • get_data.R: Pull raw input data from figshare
  • update_fusion_output.R: Updates obsolete Hugo gene symbols in raw input data
  • driver_fusions.R: Driver fusion results from cytogenetics/literature search
  • venn_diagram.R: Creates venn diagram of driver fusions
  • summary: Creates combined excel sheet with Fusion detection/filtering pipeline + driver fusions
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