DEE2 is the world's largest set of processed RNA-seq data (http://dee2.io). We made use of this dataset by curating human disease related data into gene sets for use in enrichment analysis with tools such as GSEA and mitch. In this pilot project, our focus was on human diseases including diabetes, heart disease, epilepsy and viral infection (SARS/MERS/SARS-CoV-2).
| Library | No. sets |
|---|---|
| Epilepsy | 12 |
| Diabetes | 129 |
| Heart disease | 50 |
| SARS,MERS,SARS-CoV-2 | 66 |
These gene sets are available in GMT format from the DEE2 website
Methods used to generate the gene sets are given here.
Contributions are welcome! Follow the documentation and get involved.