diff --git a/packages/core/src/config/functions.ts b/packages/core/src/config/functions.ts
index 6af92b10f..565e8c2c2 100644
--- a/packages/core/src/config/functions.ts
+++ b/packages/core/src/config/functions.ts
@@ -33,7 +33,7 @@ const functions = {
     oklab: { unit: '' },
     oklch: { unit: '' },
     'light-dark': { unit: '' },
-    clamp: { unit: '' },
+    clamp: { transformer: ['core.math-fn', { name: 'clamp' }] },
     repeat: { unit: '' },
     'linear-gradient': {},
     'radial-gradient': {},
diff --git a/packages/core/src/function-transformers/core.math-fn.ts b/packages/core/src/function-transformers/core.math-fn.ts
new file mode 100644
index 000000000..0d2eff24e
--- /dev/null
+++ b/packages/core/src/function-transformers/core.math-fn.ts
@@ -0,0 +1,61 @@
+import { SyntaxRule } from '../syntax-rule'
+
+/**
+ * Transformer for CSS math comparison functions (clamp/min/max).
+ *
+ * Each top-level comma-separated argument is itself a `<calc-sum>` per
+ * CSS Values Module Level 4. Browsers reject bare arithmetic like
+ * `clamp(1.5rem, 2vw+1rem, 2.25rem)`; the middle arg must be wrapped in
+ * `calc()`. This transformer auto-wraps any argument that contains an
+ * infix arithmetic operator and isn't already a calc()/min()/max()/clamp()/var().
+ *
+ * The function name is passed via the transformer data tuple, e.g.
+ * `clamp: { transformer: ['core.math-fn', { name: 'clamp' }] }`.
+ */
+export default function coreMathFn(
+    this: SyntaxRule,
+    value: string,
+    _bypassVariableNames: string[],
+    data?: { name: string }
+) {
+    const fnName = data?.name ?? ''
+
+    // Walk top-level commas, preserving the exact original substring of each
+    // argument (including its surrounding whitespace) and the comma separators.
+    const tokens: string[] = []
+    let depth = 0
+    let start = 0
+    for (let i = 0; i < value.length; i++) {
+        const c = value[i]
+        if (c === '(') depth++
+        else if (c === ')') depth--
+        else if (c === ',' && depth === 0) {
+            tokens.push(value.slice(start, i))
+            tokens.push(',')
+            start = i + 1
+        }
+    }
+    tokens.push(value.slice(start))
+
+    const out = tokens.map((part) => {
+        if (part === ',') return part
+        const trimmed = part.trim()
+        if (!trimmed) return part
+        if (/^(?:calc|clamp|min|max|var)\(/.test(trimmed)) return part
+        if (/[a-zA-Z0-9%)]\s*[+\-*/]\s*[a-zA-Z0-9(.]/.test(trimmed)) {
+            // CSS calc() requires whitespace around `+` and `-` (per the spec);
+            // `*` and `/` allow no whitespace. Normalize unary signs first
+            // (e.g. leading `-1rem`) before inserting spaces.
+            const spaced = trimmed.replace(
+                /([a-zA-Z0-9%)])\s*([+\-])\s*([a-zA-Z0-9(.])/g,
+                '$1 $2 $3'
+            )
+            const leadingWs = part.match(/^\s*/)![0]
+            const trailingWs = part.match(/\s*$/)![0]
+            return `${leadingWs}calc(${spaced})${trailingWs}`
+        }
+        return part
+    })
+
+    return `${fnName}(${out.join('')})`
+}
diff --git a/packages/core/src/function-transformers/index.ts b/packages/core/src/function-transformers/index.ts
index ea0cec1ad..735b1cec1 100644
--- a/packages/core/src/function-transformers/index.ts
+++ b/packages/core/src/function-transformers/index.ts
@@ -1,8 +1,10 @@
 import coreCalc from './core.calc'
+import coreMathFn from './core.math-fn'
 import coreVariable from './core.variable'
 
 const functionTransformers = {
     'core.calc': coreCalc,
+    'core.math-fn': coreMathFn,
     'core.variable': coreVariable,
 }
 
diff --git a/packages/core/tests/issue-358-clamp.test.ts b/packages/core/tests/issue-358-clamp.test.ts
new file mode 100644
index 000000000..a53e3ee5c
--- /dev/null
+++ b/packages/core/tests/issue-358-clamp.test.ts
@@ -0,0 +1,47 @@
+import { describe, test, expect } from 'vitest'
+import { MasterCSS, config as defaultConfig } from '../src'
+
+describe('issue #358: clamp() with bare arithmetic in middle arg', () => {
+    test('font-size:clamp(1.5rem,2vw+1rem,2.25rem) auto-wraps the arithmetic arg in calc()', () => {
+        const css = new MasterCSS(undefined, defaultConfig)
+        const rule = css.create('font-size:clamp(1.5rem,2vw+1rem,2.25rem)')
+        expect(rule).toBeDefined()
+        // calc() must have whitespace around + and - per CSS spec, otherwise the browser rejects it.
+        expect(rule?.text).toMatch(/font-size:clamp\(1\.5rem,\s*calc\(2vw \+ 1rem\),\s*2\.25rem\)/)
+    })
+
+    test('clamp() handles whitespace in input correctly', () => {
+        const css = new MasterCSS(undefined, defaultConfig)
+        const rule = css.create('font-size:clamp(1rem, 2vw + 1rem, 3rem)')
+        expect(rule?.text).toMatch(/clamp\(\s*1rem\s*,\s*calc\(2vw\s*\+\s*1rem\)\s*,\s*3rem\s*\)/)
+    })
+
+    test('clamp() args that are already calc() are not double-wrapped', () => {
+        const css = new MasterCSS(undefined, defaultConfig)
+        const rule = css.create('font-size:clamp(1rem,calc(2vw+1rem),3rem)')
+        expect(rule?.text).toMatch(/clamp\(1rem,calc\(2vw\s*\+\s*1rem\),3rem\)/)
+        expect(rule?.text).not.toContain('calc(calc(')
+    })
+
+    test('clamp() with negative leading values still parses correctly', () => {
+        const css = new MasterCSS(undefined, defaultConfig)
+        const rule = css.create('font-size:clamp(-1rem,2vw,3rem)')
+        // Single token with leading minus is a sign, not arithmetic — no calc wrapping.
+        expect(rule?.text).toContain('clamp(-1rem,2vw,3rem)')
+    })
+
+    test('clamp() with calc() wrapper still works (regression)', () => {
+        const css = new MasterCSS(undefined, defaultConfig)
+        const rule = css.create('font-size:clamp(1.5rem,calc(2vw+1rem),2.25rem)')
+        expect(rule).toBeDefined()
+        expect(rule?.text).toContain('font-size')
+        expect(rule?.text).toContain('clamp(')
+    })
+
+    test('plain clamp() without arithmetic still works', () => {
+        const css = new MasterCSS(undefined, defaultConfig)
+        const rule = css.create('font-size:clamp(1rem,2vw,3rem)')
+        expect(rule).toBeDefined()
+        expect(rule?.text).toContain('clamp(1rem,2vw,3rem)')
+    })
+})