diff --git a/changelog.d/15428.bugfix b/changelog.d/15428.bugfix
new file mode 100644
index 000000000000..1083f00b81d6
--- /dev/null
+++ b/changelog.d/15428.bugfix
@@ -0,0 +1 @@
+Disable loading `RefreshTokenServlet` (`/_matrix/client/(r0|v3|unstable)/refresh`) on workers.
\ No newline at end of file
diff --git a/synapse/rest/client/login.py b/synapse/rest/client/login.py
index b7e9c8f6b572..32c2f5ce0c5e 100644
--- a/synapse/rest/client/login.py
+++ b/synapse/rest/client/login.py
@@ -670,7 +670,10 @@ async def on_GET(self, request: SynapseRequest) -> None:
 
 def register_servlets(hs: "HomeServer", http_server: HttpServer) -> None:
     LoginRestServlet(hs).register(http_server)
-    if hs.config.registration.refreshable_access_token_lifetime is not None:
+    if (
+        hs.config.worker.worker_app is None
+        and hs.config.registration.refreshable_access_token_lifetime is not None
+    ):
         RefreshTokenServlet(hs).register(http_server)
     SsoRedirectServlet(hs).register(http_server)
     if hs.config.cas.cas_enabled: