This repository provides the omeprazole physiological based pharmacokinetics/pharmacodynamics model (PBPK/PD).
The model is distributed as SBML available from omeprazole_body_flat.xml with
corresponding SBML4humans model report at https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/matthiaskoenig/omeprazole-model/main/models/omeprazole_body_flat.xml
The liver submodel is available from omeprazole_liver.xml with corresponding SBML4humans report at
https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/matthiaskoenig/omeprazole-model/main/models/omeprazole_liver.xml
The kidney submodel is available from omeprazole_kidney.xml with corresponding SBML4humans report at
https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/matthiaskoenig/omeprazole-model/main/models/omeprazole_kidney.xml
The stomach submodel is available from omeprazole_stomach.xml with corresponding SBML4humans report at
https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/matthiaskoenig/omeprazole-model/main/models/omeprazole_stomach.xml
The whole-body submodel is available from omeprazole_body.xml with corresponding SBML4humans report at
https://sbml4humans.de/model_url?url=https://raw.githubusercontent.com/matthiaskoenig/omeprazole-model/main/models/omeprazole_body.xml
König, Matthias, & Balci, Sükrü. (2021).
Omeprazole physiological based pharmacokinetics/pharmacodynamics model (PBPK/PD) (0.8.0).
Zenodo. https://doi.org/10.5281/zenodo.5575750
- Source Code: LGPLv3
- Documentation: CC BY-SA 4.0
- Models: CC BY-SA 4.0
The omeprazole-model source is released under both the GPL and LGPL licenses version 2 or later. You may choose which license you choose to use the software under.
This program is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License or the GNU Lesser General Public License as published by the Free Software Foundation, either version 2 of the License, or (at your option) any later version.
This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details.
Matthias König is supported by the Federal Ministry of Education and Research (BMBF, Germany) within the research network Systems Medicine of the Liver (LiSyM, grant number 031L0054) and by the German Research Foundation (DFG) within the Research Unit Programme FOR 5151 QuaLiPerF (Quantifying Liver Perfusion-Function Relationship in Complex Resection - A Systems Medicine Approach) by grant number 436883643.
© 2020-2021 Matthias König