diff --git a/pandas/tests/tools/test_to_datetime.py b/pandas/tests/tools/test_to_datetime.py
index 93fe9b05adb4f5..ffcc41ed2263c6 100644
--- a/pandas/tests/tools/test_to_datetime.py
+++ b/pandas/tests/tools/test_to_datetime.py
@@ -613,6 +613,7 @@ def test_to_datetime_mixed_date_and_string(self, format):
         expected = DatetimeIndex(["2020-01-01", "2020-01-02"])
         tm.assert_index_equal(res, expected)
 
+    @pytest.skipif(tm.IS_PYPY, reason="PyPy crashes creating DatimeIndex with timezone")
     @pytest.mark.parametrize(
         "fmt",
         ["%Y-%d-%m %H:%M:%S%z", "%Y-%m-%d %H:%M:%S%z"],