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+### Introduction
+
+npReader is a tool to facilitate real-time conversion and analysis of Nanopore sequencing 
+data. Its source code is part of [Japsa](https://github.com/mdcao/japsa) package.
+
+### Quick installation guide
+
+######Under Linux/Mac
+
+1.Install JHI5 using the packaging tool of your operating system distribution. For example, under Debian/Ubuntu
+ 
+    sudo apt-get install libjhdf5-jni
+
+2.Obtain the source code, compile and install
+
+    git clone https://github.com/mdcao/japsa
+    cd japsa
+    make install JLP=/usr/lib/jni \
+     [INSTALL_DIR=~/.usr/local \] 
+     [MXMEM=7000m \] 
+     [SERVER=true \] 
+
+Change the JLP directive to point to where JHI5 is installed if needed.
+
+3.Set the environment variable PATH to include the installation directory, eg,
+
+    set PATH=~/.usr/local/bin:$PATH
+
+4.Usage information
+
+    jsa.np.f5reader --help
+  
+######On any OSs
+
+1.Install JNI from https://www.hdfgroup.org/products/java/JNI/jhi5/index.html 
+
+2.Download pre-compiled Japsa of the latest release from https://github.com/mdcao/japsa/releases
+
+3.Unzip the  package, and run install.sh (for Linux/Mac) or install.bat (for Windows) and follow the prompt.
+
+
+### Documentation
+
+Detailed usage of npReader including setting up streaming analysis of nanopore sequencing in
+genuain  real-time can be found from http://japsa.readthedocs.org/en/latest/tools/jsa.np.f5reader.html