diff --git a/.travis.yml b/.travis.yml
index 480ca23..466cdf4 100644
--- a/.travis.yml
+++ b/.travis.yml
@@ -1,7 +1,6 @@
 language: python
 cache: pip
 python:
-    - 3.5
     - 3.6
     - 3.7
     - 3.8
diff --git a/CHANGES.rst b/CHANGES.rst
index c8d0621..ad8df80 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -5,7 +5,7 @@ Changelog
 0.45 (unreleased)
 -----------------
 
-- Nothing changed yet.
+- Drop Python 3.5 support.
 
 
 0.44 (2020-10-03)
diff --git a/appveyor.yml b/appveyor.yml
index aba77ee..1745964 100644
--- a/appveyor.yml
+++ b/appveyor.yml
@@ -4,7 +4,6 @@ environment:
   matrix:
     # https://www.appveyor.com/docs/installed-software#python lists available
     # versions
-    - PYTHON: "C:\\Python35"
     - PYTHON: "C:\\Python36"
     - PYTHON: "C:\\Python37"
     - PYTHON: "C:\\Python38"
diff --git a/setup.py b/setup.py
index 16baf7d..867e78c 100755
--- a/setup.py
+++ b/setup.py
@@ -44,7 +44,6 @@
         'Operating System :: OS Independent',
         'Programming Language :: Python',
         'Programming Language :: Python :: 3',
-        'Programming Language :: Python :: 3.5',
         'Programming Language :: Python :: 3.6',
         'Programming Language :: Python :: 3.7',
         'Programming Language :: Python :: 3.8',
@@ -55,7 +54,7 @@
 
     py_modules=['check_manifest'],
     zip_safe=False,
-    python_requires=">=3.5",
+    python_requires=">=3.6",
     install_requires=[
         'pep517',
         'setuptools',
diff --git a/tox.ini b/tox.ini
index a2d6d6a..85de074 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,6 +1,6 @@
 [tox]
 envlist =
-    py35,py36,py37,py38,pypy3,flake8
+    py36,py37,py38,pypy3,flake8
 
 [testenv]
 passenv = LANG LC_CTYPE LC_ALL MSYSTEM