diff --git a/src/adapter/breakpoints/breakpointBase.ts b/src/adapter/breakpoints/breakpointBase.ts
index 42b972b6f..19471805d 100644
--- a/src/adapter/breakpoints/breakpointBase.ts
+++ b/src/adapter/breakpoints/breakpointBase.ts
@@ -518,6 +518,7 @@ export abstract class Breakpoint {
           bp.args.location.scriptId === script.scriptId &&
           lcEqual(bp.args.location, lineColumn)) ||
         (script.url &&
+          !script.hasSourceURL &&
           isSetByUrl(bp.args) &&
           (bp.args.urlRegex
             ? new RegExp(bp.args.urlRegex).test(script.url)
@@ -560,8 +561,9 @@ export abstract class Breakpoint {
 
   protected async _setForSpecific(thread: Thread, script: ISourceScript, lineColumn: LineColumn) {
     // prefer to set on script URL for non-anonymous scripts, since url breakpoints
-    // will survive and be hit on reload.
-    if (script.url) {
+    // will survive and be hit on reload. But don't set if the script has
+    // a source URL, since V8 doesn't resolve these
+    if (script.url && !script.hasSourceURL) {
       return this._setByUrl(thread, script.url, lineColumn);
     } else {
       return this._setByScriptId(thread, script, lineColumn);
diff --git a/src/adapter/source.ts b/src/adapter/source.ts
index 77c4f3f9d..74776eea3 100644
--- a/src/adapter/source.ts
+++ b/src/adapter/source.ts
@@ -384,6 +384,7 @@ export interface IWasmLocationProvider extends ISourceLocationProvider {
 export interface ISourceScript {
   executionContextId: Cdp.Runtime.ExecutionContextId;
   scriptId: Cdp.Runtime.ScriptId;
+  hasSourceURL: boolean;
   url: string;
 }
 
diff --git a/src/adapter/threads.ts b/src/adapter/threads.ts
index 08d0f2fdd..eb1272238 100644
--- a/src/adapter/threads.ts
+++ b/src/adapter/threads.ts
@@ -36,7 +36,14 @@ import * as objectPreview from './objectPreview';
 import { PreviewContextType, getContextForType } from './objectPreview/contexts';
 import { ExpectedPauseReason, IPausedDetails, StepDirection } from './pause';
 import { SmartStepper } from './smartStepping';
-import { ISourceWithMap, IUiLocation, Source, base1To0, isSourceWithWasm } from './source';
+import {
+  ISourceScript,
+  ISourceWithMap,
+  IUiLocation,
+  Source,
+  base1To0,
+  isSourceWithWasm,
+} from './source';
 import { IPreferredUiLocation, SourceContainer } from './sourceContainer';
 import { InlinedFrame, StackFrame, StackTrace, isStackFrameElement } from './stackTrace';
 import {
@@ -69,10 +76,7 @@ export class ExecutionContext {
   }
 }
 
-export type Script = {
-  url: string;
-  scriptId: string;
-  executionContextId: number;
+export type Script = ISourceScript & {
   source: Promise<Source>;
   resolvedSource?: Source;
 };
@@ -1515,6 +1519,7 @@ export class Thread implements IVariableStoreLocationProvider {
         prevSource.addScript({
           scriptId: event.scriptId,
           url: event.url,
+          hasSourceURL: !!event.hasSourceURL,
           executionContextId: event.executionContextId,
         });
         return prevSource;
@@ -1565,6 +1570,7 @@ export class Thread implements IVariableStoreLocationProvider {
       source.addScript({
         scriptId: event.scriptId,
         url: event.url,
+        hasSourceURL: !!event.hasSourceURL,
         executionContextId: event.executionContextId,
       });
 
@@ -1573,6 +1579,7 @@ export class Thread implements IVariableStoreLocationProvider {
 
     const script: Script = {
       url: event.url,
+      hasSourceURL: !!event.hasSourceURL,
       scriptId: event.scriptId,
       executionContextId: event.executionContextId,
       source: createSource(),