Check out http://mklabs.github.com/gh-issues-widget to see this in action.
A simple jQuery plugin using a bit of Github API v3, underscore micro templates, and github flavored markdown to fetch and display issues inline in websites.
It can be super handy for static website using github as a backend. Why not using github issues as a basic comment system ? Here's an attempt.
Will soon add more words here
And this is far from being stable, robust or anything like that. Tests and further docs will be added soon, maybe.