diff --git a/apps/system/js/accessibility.js b/apps/system/js/accessibility.js
index 6026b9f8c5e4..e2e2b73b322c 100644
--- a/apps/system/js/accessibility.js
+++ b/apps/system/js/accessibility.js
@@ -105,6 +105,14 @@
         SettingsListener.observe(settingKey, this.settings[settingKey],
           function observe(aValue) {
             this.settings[settingKey] = aValue;
+
+            // Show/Hide Accessibility Panel whenever volume buttons
+            // trigger Screen Reader
+            if (settingKey === 'accessibility.screenreader') {
+              SettingsListener.getSettingsLock().set({
+                'accessibility.show-settings': aValue
+              });
+            }
           }.bind(this));
       }, this);
     },
diff --git a/tests/python/gaia-ui-tests/gaiatest/tests/accessibility/system/manifest.ini b/tests/python/gaia-ui-tests/gaiatest/tests/accessibility/system/manifest.ini
index 501ce9e73917..cff71ecd5a63 100644
--- a/tests/python/gaia-ui-tests/gaiatest/tests/accessibility/system/manifest.ini
+++ b/tests/python/gaia-ui-tests/gaiatest/tests/accessibility/system/manifest.ini
@@ -6,3 +6,4 @@ b2g = true
 [test_a11y_utility_tray_settings.py]
 [test_a11y_utility_tray_visibility.py]
 [test_a11y_volume_buttons.py]
+[test_a11y_volume_buttons_panel_visibility.py]
diff --git a/tests/python/gaia-ui-tests/gaiatest/tests/accessibility/system/test_a11y_volume_buttons_panel_visibility.py b/tests/python/gaia-ui-tests/gaiatest/tests/accessibility/system/test_a11y_volume_buttons_panel_visibility.py
new file mode 100644
index 000000000000..df87194e40ac
--- /dev/null
+++ b/tests/python/gaia-ui-tests/gaiatest/tests/accessibility/system/test_a11y_volume_buttons_panel_visibility.py
@@ -0,0 +1,53 @@
+# This Source Code Form is subject to the terms of the Mozilla Public
+# License, v. 2.0. If a copy of the MPL was not distributed with this
+# file, You can obtain one at http://mozilla.org/MPL/2.0/.
+
+import time
+
+from gaiatest import GaiaTestCase
+from gaiatest.apps.settings.app import Settings
+
+
+class TestVolumeButtonsAccessibility(GaiaTestCase):
+
+    def setUp(self):
+        GaiaTestCase.setUp(self)
+
+        self.settings = Settings(self.marionette)
+        self.settings.launch()
+
+    def toggle_screen_reader(self):
+        self.marionette.switch_to_frame()
+
+        self.device.press_release_volume_up_then_down_n_times(3)
+        time.sleep(3)
+        self.device.press_release_volume_up_then_down_n_times(3)
+
+        self.apps.switch_to_displayed_app()
+
+    def test_a11y_volume_buttons(self):
+
+        # Panel should not be visible by default
+        self.assertFalse(self.data_layer.get_setting('accessibility.show-settings'))
+        self.assertFalse(self.is_element_displayed(
+            *self.settings._accessibility_menu_item_locator))
+        self.assertTrue(self.accessibility.is_hidden(self.marionette.find_element(
+            *self.settings._accessibility_menu_item_locator)))
+
+        self.toggle_screen_reader()
+
+        # Panel should become visible after screen reader turned ON
+        self.assertTrue(self.data_layer.get_setting('accessibility.show-settings'))
+        self.assertTrue(self.is_element_displayed(
+            *self.settings._accessibility_menu_item_locator))
+        self.assertTrue(self.accessibility.is_visible(self.marionette.find_element(
+            *self.settings._accessibility_menu_item_locator)))
+
+        self.toggle_screen_reader()
+
+        # Panel should not be visible again
+        self.assertFalse(self.data_layer.get_setting('accessibility.show-settings'))
+        self.assertFalse(self.is_element_displayed(
+            *self.settings._accessibility_menu_item_locator))
+        self.assertTrue(self.accessibility.is_hidden(self.marionette.find_element(
+            *self.settings._accessibility_menu_item_locator)))
diff --git a/tests/python/gaia-ui-tests/gaiatest/tests/tbpl-manifest.ini b/tests/python/gaia-ui-tests/gaiatest/tests/tbpl-manifest.ini
index 89f3bed6fdec..4886ba6340e6 100644
--- a/tests/python/gaia-ui-tests/gaiatest/tests/tbpl-manifest.ini
+++ b/tests/python/gaia-ui-tests/gaiatest/tests/tbpl-manifest.ini
@@ -33,6 +33,7 @@ disabled = Bug 1022132 Intermittent Failure on TBPL
 [accessibility/system/test_a11y_utility_tray_settings.py]
 [accessibility/system/test_a11y_utility_tray_visibility.py]
 [accessibility/system/test_a11y_volume_buttons.py]
+[accessibility/system/test_a11y_volume_buttons_panel_visibility.py]
 
 [functional/browser/test_browser_bookmark.py]
 [functional/browser/test_browser_lan.py]