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mr-eyes/MEM-codons-optimizer

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codons-optimizer

Description

  • Load fasta DNA of virus and host.
  • Convert DNA of virus and host to protein sequence.
  • Find all Maximal Exact Matches from virus in host protein sequences.
  • Get the mapped DNA intervals in virus and host.
  • Get the host DNA to be replaced.
  • Replace the virus DNA fragement with the host DNA fragement.
  • Write the optimized virus sequence to disk.

Run

python main.py virus_dna.fasta host_dna.fasta

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A tool to perform codons optimization using the maximal exact match technique.

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