Tools for computational analysis of single nuclei methylC-Seq data, as described in Luo, Keown et al. (2017)
Switch branches/tags
Nothing to show
Clone or download
Fetching latest commit…
Cannot retrieve the latest commit at this time.
Permalink
Failed to load latest commit information.
__pycache__
README.md
backspin.py
bin_allc_files.py
preproc_and_TSNE.py
run_snmcseq
single_cell_filter.pl

README.md

Single Cell Methylomes Identify Neuronal Subtypes and Regulatory Elements in Mammalian Cortex

Science 357, 600 (2017)

More information at the project website: http://brainome.org

Chongyuan Luo1,2,†, Christopher L. Keown3,†, Laurie Kurihara4, Jingtian Zhou1,5, Yupeng He1,5, Junhao Li3, Rosa Castanon1, Jacinta Lucero6, Joseph R. Nery1, Justin Sandoval1, Brian Bui6, Terrence J. Sejnowski2,6, Timothy Harkins4, Eran A. Mukamel3,*, M. Margarita Behrens6,*, Joseph R. Ecker1,2,*

  1. Genomic Analysis Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, United States.
  2. Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, United States.
  3. Department of Cognitive Science, University of California, San Diego, La Jolla, CA 92037, United States.
  4. Swift Biosciences Inc, 58 Parkland Plaza, Ste. 100, Ann Arbor, MI 48103, United States.
  5. Bioinformatics Program, University of California, San Diego, La Jolla, CA 92093, United States.
  6. Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, United States.

Contact: emukamel [at] ucsd [dot] edu; mbehrens [at] salk [dot] edu; ecker [at] salk [dot] edu

Data browsers:

  • Data download
    • GEO GSE97179

    snmcseq

    Tools for computational analysis of single nuclei methylC-Seq data, as described in Luo, Keown et al. (2017)

    Contact: Chris Keown (ckeown @ ucsd.edu), Eran Mukamel (emukamel @ ucsd.edu)

    Mukamel lab: http://brainome.ucsd.edu

    See also: Methylpy https://github.com/yupenghe/methylpy

    Mukamel lab: http://brainome.ucsd.edu