diff --git a/Changes.md b/Changes.md
index 49af77f97..b36fe34a7 100644
--- a/Changes.md
+++ b/Changes.md
@@ -7,6 +7,7 @@ you spot any mistakes.
 ## HEAD
 
 * Add `localInfile` option to control `LOAD DATA LOCAL INFILE`
+* Add new Amazon RDS Root 2019 CA to Amazon RDS SSL profile #2280
 * Add new error codes up to MySQL 5.7.29
 * Fix early detection of bad callback to `connection.query`
 * Support Node.js 12.x #2211
diff --git a/lib/protocol/constants/ssl_profiles.js b/lib/protocol/constants/ssl_profiles.js
index e76b954e1..3389c3a37 100644
--- a/lib/protocol/constants/ssl_profiles.js
+++ b/lib/protocol/constants/ssl_profiles.js
@@ -71,6 +71,43 @@ exports['Amazon RDS'] = {
     + '/40NawZfTUU=\n'
     + '-----END CERTIFICATE-----\n',
 
+    /**
+     * Amazon RDS global root CA 2019 to 2024
+     *
+     *   CN = Amazon RDS Root 2019 CA
+     *   OU = Amazon RDS
+     *   O = Amazon Web Services, Inc.
+     *   L = Seattle
+     *   ST = Washington
+     *   C = US
+     *   P = 2019-08-22T17:08:50Z/2024-08-22T17:08:50Z
+     *   F = D4:0D:DB:29:E3:75:0D:FF:A6:71:C3:14:0B:BF:5F:47:8D:1C:80:96
+     */
+    '-----BEGIN CERTIFICATE-----\n'
+    + 'MIIEBjCCAu6gAwIBAgIJAMc0ZzaSUK51MA0GCSqGSIb3DQEBCwUAMIGPMQswCQYD\n'
+    + 'VQQGEwJVUzEQMA4GA1UEBwwHU2VhdHRsZTETMBEGA1UECAwKV2FzaGluZ3RvbjEi\n'
+    + 'MCAGA1UECgwZQW1hem9uIFdlYiBTZXJ2aWNlcywgSW5jLjETMBEGA1UECwwKQW1h\n'
+    + 'em9uIFJEUzEgMB4GA1UEAwwXQW1hem9uIFJEUyBSb290IDIwMTkgQ0EwHhcNMTkw\n'
+    + 'ODIyMTcwODUwWhcNMjQwODIyMTcwODUwWjCBjzELMAkGA1UEBhMCVVMxEDAOBgNV\n'
+    + 'BAcMB1NlYXR0bGUxEzARBgNVBAgMCldhc2hpbmd0b24xIjAgBgNVBAoMGUFtYXpv\n'
+    + 'biBXZWIgU2VydmljZXMsIEluYy4xEzARBgNVBAsMCkFtYXpvbiBSRFMxIDAeBgNV\n'
+    + 'BAMMF0FtYXpvbiBSRFMgUm9vdCAyMDE5IENBMIIBIjANBgkqhkiG9w0BAQEFAAOC\n'
+    + 'AQ8AMIIBCgKCAQEArXnF/E6/Qh+ku3hQTSKPMhQQlCpoWvnIthzX6MK3p5a0eXKZ\n'
+    + 'oWIjYcNNG6UwJjp4fUXl6glp53Jobn+tWNX88dNH2n8DVbppSwScVE2LpuL+94vY\n'
+    + '0EYE/XxN7svKea8YvlrqkUBKyxLxTjh+U/KrGOaHxz9v0l6ZNlDbuaZw3qIWdD/I\n'
+    + '6aNbGeRUVtpM6P+bWIoxVl/caQylQS6CEYUk+CpVyJSkopwJlzXT07tMoDL5WgX9\n'
+    + 'O08KVgDNz9qP/IGtAcRduRcNioH3E9v981QO1zt/Gpb2f8NqAjUUCUZzOnij6mx9\n'
+    + 'McZ+9cWX88CRzR0vQODWuZscgI08NvM69Fn2SQIDAQABo2MwYTAOBgNVHQ8BAf8E\n'
+    + 'BAMCAQYwDwYDVR0TAQH/BAUwAwEB/zAdBgNVHQ4EFgQUc19g2LzLA5j0Kxc0LjZa\n'
+    + 'pmD/vB8wHwYDVR0jBBgwFoAUc19g2LzLA5j0Kxc0LjZapmD/vB8wDQYJKoZIhvcN\n'
+    + 'AQELBQADggEBAHAG7WTmyjzPRIM85rVj+fWHsLIvqpw6DObIjMWokpliCeMINZFV\n'
+    + 'ynfgBKsf1ExwbvJNzYFXW6dihnguDG9VMPpi2up/ctQTN8tm9nDKOy08uNZoofMc\n'
+    + 'NUZxKCEkVKZv+IL4oHoeayt8egtv3ujJM6V14AstMQ6SwvwvA93EP/Ug2e4WAXHu\n'
+    + 'cbI1NAbUgVDqp+DRdfvZkgYKryjTWd/0+1fS8X1bBZVWzl7eirNVnHbSH2ZDpNuY\n'
+    + '0SBd8dj5F6ld3t58ydZbrTHze7JJOd8ijySAp4/kiu9UfZWuTPABzDa/DSdz9Dk/\n'
+    + 'zPW4CXXvhLmE02TA9/HeCw3KEHIwicNuEfw=\n'
+    + '-----END CERTIFICATE-----\n',
+
     /**
      * Amazon RDS ap-northeast-1 certificate CA 2015 to 2020
      *