diff --git a/packages/nodes-base/credentials/ERPNextApi.credentials.ts b/packages/nodes-base/credentials/ERPNextApi.credentials.ts
index d94210600e95a..1ad997f74c802 100644
--- a/packages/nodes-base/credentials/ERPNextApi.credentials.ts
+++ b/packages/nodes-base/credentials/ERPNextApi.credentials.ts
@@ -20,13 +20,51 @@ export class ERPNextApi implements ICredentialType {
 			type: 'string' as NodePropertyTypes,
 			default: '',
 		},
+		{
+			displayName: 'Environment',
+			name: 'environment',
+			type: 'options' as NodePropertyTypes,
+			default: 'cloudHosted',
+			options: [
+				{
+					name: 'Cloud-hosted',
+					value: 'cloudHosted',
+				},
+				{
+					name: 'Self-hosted',
+					value: 'selfHosted',
+				},
+			],
+		},
 		{
 			displayName: 'Subdomain',
 			name: 'subdomain',
 			type: 'string' as NodePropertyTypes,
 			default: '',
 			placeholder: 'n8n',
-			description: 'ERPNext subdomain. For instance, entering n8n will make the url look like: https://n8n.erpnext.com/.',
+			description: 'Subdomain of cloud-hosted ERPNext instance. For example, "n8n" is the subdomain in: <code>https://n8n.erpnext.com</code>',
+			displayOptions: {
+				show: {
+					environment: [
+						'cloudHosted',
+					],
+				},
+			},
+		},
+		{
+			displayName: 'Domain',
+			name: 'domain',
+			type: 'string' as NodePropertyTypes,
+			default: '',
+			placeholder: 'https://www.mydomain.com',
+			description: 'Fully qualified domain name of self-hosted ERPNext instance.',
+			displayOptions: {
+				show: {
+					environment: [
+						'selfHosted',
+					],
+				},
+			},
 		},
 	];
 }
diff --git a/packages/nodes-base/nodes/ERPNext/GenericFunctions.ts b/packages/nodes-base/nodes/ERPNext/GenericFunctions.ts
index 08de44e8e08d0..4a85c0064ab26 100644
--- a/packages/nodes-base/nodes/ERPNext/GenericFunctions.ts
+++ b/packages/nodes-base/nodes/ERPNext/GenericFunctions.ts
@@ -24,8 +24,8 @@ export async function erpNextApiRequest(
 	uri?: string,
 	option: IDataObject = {},
 ) {
-
-	const credentials = this.getCredentials('erpNextApi');
+	const credentials = this.getCredentials('erpNextApi') as ERPNextApiCredentials;
+	const baseUrl = getBaseUrl(credentials);
 
 	if (credentials === undefined) {
 		throw new NodeOperationError(this.getNode(), 'No credentials got returned!');
@@ -40,7 +40,7 @@ export async function erpNextApiRequest(
 		method,
 		body,
 		qs: query,
-		uri: uri || `https://${credentials.subdomain}.erpnext.com${resource}`,
+		uri: uri || `${baseUrl}${resource}`,
 		json: true,
 	};
 
@@ -56,13 +56,12 @@ export async function erpNextApiRequest(
 	try {
 		return await this.helpers.request!(options);
 	} catch (error) {
-
 		if (error.statusCode === 403) {
-			throw new NodeApiError(this.getNode(), { message: `DocType unavailable.` });
+			throw new NodeApiError(this.getNode(), { message: 'DocType unavailable.' });
 		}
 
 		if (error.statusCode === 307) {
-			throw new NodeApiError(this.getNode(), { message:`Please ensure the subdomain is correct.` });
+			throw new NodeApiError(this.getNode(), { message: 'Please ensure the subdomain is correct.' });
 		}
 
 		throw new NodeApiError(this.getNode(), error);
@@ -95,3 +94,19 @@ export async function erpNextApiRequestAllItems(
 
 	return returnData;
 }
+
+/**
+ * Return the base API URL based on the user's environment.
+ */
+const getBaseUrl = ({ environment, domain, subdomain }: ERPNextApiCredentials) =>
+	environment === 'cloudHosted'
+		? `https://${subdomain}.erpnext.com`
+		: domain;
+
+type ERPNextApiCredentials = {
+	apiKey: string;
+	apiSecret: string;
+	environment: 'cloudHosted' | 'selfHosted';
+	subdomain?: string;
+	domain?: string;
+};