diff --git a/CHANGES.md b/CHANGES.md
index 415b0c51..0804d441 100644
--- a/CHANGES.md
+++ b/CHANGES.md
@@ -13,6 +13,13 @@ development source code and as such may not be routinely kept up to date.
 
 # __NEXT__
 
+## Bug fixes
+
+* We've fixed and future-proofed a compatibility bug with a third-party library
+  that can occur under very specific conditions when `nextstrain build` submits
+  AWS Batch jobs.
+  ([#261](https://github.com/nextstrain/cli/pull/261))
+
 
 # 6.2.0 (28 February 2023)
 
diff --git a/nextstrain/cli/runner/aws_batch/jobs.py b/nextstrain/cli/runner/aws_batch/jobs.py
index b79d3d84..e4729930 100644
--- a/nextstrain/cli/runner/aws_batch/jobs.py
+++ b/nextstrain/cli/runner/aws_batch/jobs.py
@@ -288,9 +288,11 @@ def override_definition(base_definition_name: str, image: str) -> str:
         derived_definition["jobDefinitionName"] = derived_definition_name
         derived_definition["containerProperties"]["image"] = image
 
-        # These are AWS-assigned keys returned by describe_job_definitions() which
+        # Remove AWS-assigned keys returned by describe_job_definitions() which
         # aren't supported as keyword arguments by register_job_definition().
-        for key in {'jobDefinitionArn', 'revision', 'status'}:
+        register_inputs = batch.meta.service_model.operation_model("RegisterJobDefinition").input_shape.members
+
+        for key in set(derived_definition) - set(register_inputs):
             del derived_definition[key]
 
         batch.register_job_definition(**derived_definition)