diff --git a/CHANGELOG.md b/CHANGELOG.md
index 6c48a0e47..360c10b7e 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -24,6 +24,7 @@ and this project adheres to [Semantic Versioning](http://semver.org/spec/v2.0.0.
 * Fancy new logo from [ZandraFagernas](https://github.com/ZandraFagernas)
 * [#286](https://github.com/nf-core/eager/issues/286) - Adds pipeline-specific profiles (loaded from nf-core configs)
 * [#310](https://github.com/nf-core/eager/issues/310) - Generalises base.config
+* [#326](https://github.com/nf-core/eager/pull/326) - Add Biopython and [xopen](https://github.com/marcelm/xopen/) dependancies  
 
 ### `Fixed`
 
diff --git a/environment.yml b/environment.yml
index a1eb6c206..be57fbf86 100644
--- a/environment.yml
+++ b/environment.yml
@@ -35,4 +35,6 @@ dependencies:
   - bioconda::sexdeterrmine=1.1.1
   - bioconda::multivcfanalyzer=0.85.1
   - bioconda::hops=0.33
+  - conda-forge::biopython=1.75
+  - conda-forge::xopen=0.8.4
   #Missing Schmutzi,snpAD