ABDS: Tool Suite for Analyzing Biologically Diverse Samples
We developed the ABDS tool suite specifically for analyzing biologically diverse samples. Mechanism-integrated group-wise pre-imputation is designed to recruit signature genes that represent informative missingness, a cosine-based one-sample test is extended to detect downregulated signature genes, and a unified heatmap is designed to display multiple phenotypic groups. We discuss the methodological principles and demonstrate the effectiveness of three analytics tools, supported by comparative evaluations and biomedical showcases.
You can install the latest version of ABDS from GitHub by
devtools::install_github("niccolodpdu/ABDS")
https://htmlpreview.github.io/?https://github.com/niccolodpdu/ABDS/blob/master/vignette.html
Some features in this vignette may not be properly displayed online. It's recommended to download the vignette to your local side.