diff --git a/lib/internal/bootstrap/pre_execution.js b/lib/internal/bootstrap/pre_execution.js
index 8de57a5666131f..c306de7db630f4 100644
--- a/lib/internal/bootstrap/pre_execution.js
+++ b/lib/internal/bootstrap/pre_execution.js
@@ -13,6 +13,7 @@ const {
 const {
   getOptionValue,
   getEmbedderOptions,
+  refreshOptions,
 } = require('internal/options');
 const { reconnectZeroFillToggle } = require('internal/buffer');
 const {
@@ -26,6 +27,8 @@ const { ERR_MANIFEST_ASSERT_INTEGRITY } = require('internal/errors').codes;
 const assert = require('internal/assert');
 
 function prepareMainThreadExecution(expandArgv1 = false) {
+  refreshRuntimeOptions();
+
   // TODO(joyeecheung): this is also necessary for workers when they deserialize
   // this toggle from the snapshot.
   reconnectZeroFillToggle();
@@ -86,6 +89,10 @@ function prepareMainThreadExecution(expandArgv1 = false) {
   initializeFrozenIntrinsics();
 }
 
+function refreshRuntimeOptions() {
+  refreshOptions();
+}
+
 function patchProcessObject(expandArgv1) {
   const binding = internalBinding('process_methods');
   binding.patchProcessObject(process);
@@ -541,6 +548,7 @@ function loadPreloadModules() {
 }
 
 module.exports = {
+  refreshRuntimeOptions,
   patchProcessObject,
   setupCoverageHooks,
   setupWarningHandler,
diff --git a/lib/internal/options.js b/lib/internal/options.js
index 01b334d4ec5614..4d92ad681a1207 100644
--- a/lib/internal/options.js
+++ b/lib/internal/options.js
@@ -36,6 +36,11 @@ function getEmbedderOptions() {
   return embedderOptions;
 }
 
+function refreshOptions() {
+  optionsMap = undefined;
+  aliasesMap = undefined;
+}
+
 function getOptionValue(optionName) {
   const options = getCLIOptionsFromBinding();
   if (optionName.startsWith('--no-')) {
@@ -68,5 +73,6 @@ module.exports = {
   },
   getOptionValue,
   getAllowUnauthorized,
-  getEmbedderOptions
+  getEmbedderOptions,
+  refreshOptions
 };