diff --git a/include/drivers/timer/system_timer.h b/include/drivers/timer/system_timer.h
index 6f5b196df49..8cf7d7a1cc1 100644
--- a/include/drivers/timer/system_timer.h
+++ b/include/drivers/timer/system_timer.h
@@ -64,8 +64,7 @@ extern int z_clock_device_ctrl(const struct device *device,
  * indicating that no future timer interrupts are expected or required
  * and that the system is permitted to enter an indefinite sleep even
  * if this could cause rollover of the internal counter (i.e. the
- * system uptime counter is allowed to be wrong, see
- * k_enable_sys_clock_always_on()).
+ * system uptime counter is allowed to be wrong
  *
  * Note also that it is conventional for the kernel to pass INT_MAX
  * for ticks if it wants to preserve the uptime tick count but doesn't
diff --git a/include/kernel.h b/include/kernel.h
index 70f94dcac2c..470f1430940 100644
--- a/include/kernel.h
+++ b/include/kernel.h
@@ -1801,8 +1801,6 @@ struct k_timer {
 	_OBJECT_TRACING_INIT \
 	}
 
-#define K_TIMER_INITIALIZER __DEPRECATED_MACRO Z_TIMER_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -2070,40 +2068,6 @@ static inline int64_t k_uptime_get(void)
 	return k_ticks_to_ms_floor64(k_uptime_ticks());
 }
 
-/**
- * @brief Enable clock always on in tickless kernel
- *
- * Deprecated.  This does nothing (it was always just a hint).  This
- * functionality has been migrated to the
- * @option{CONFIG_SYSTEM_CLOCK_SLOPPY_IDLE} config option.
- *
- * @retval prev_status Previous status of always on flag
- */
-/* LCOV_EXCL_START */
-__deprecated static inline int k_enable_sys_clock_always_on(void)
-{
-	__ASSERT(IS_ENABLED(CONFIG_SYSTEM_CLOCK_SLOPPY_IDLE),
-		 "Please use CONFIG_SYSTEM_CLOCK_SLOPPY_IDLE instead");
-
-	return !IS_ENABLED(CONFIG_SYSTEM_CLOCK_SLOPPY_IDLE);
-}
-/* LCOV_EXCL_STOP */
-
-/**
- * @brief Disable clock always on in tickless kernel
- *
- * Deprecated.  This does nothing (it was always just a hint).  This
- * functionality has been migrated to the
- * @option{CONFIG_SYSTEM_CLOCK_SLOPPY_IDLE} config option.
- */
-/* LCOV_EXCL_START */
-__deprecated static inline void k_disable_sys_clock_always_on(void)
-{
-	__ASSERT(!IS_ENABLED(CONFIG_SYSTEM_CLOCK_SLOPPY_IDLE),
-		 "Please use CONFIG_SYSTEM_CLOCK_SLOPPY_IDLE instead");
-}
-/* LCOV_EXCL_STOP */
-
 /**
  * @brief Get system uptime (32-bit version).
  *
@@ -2150,26 +2114,6 @@ static inline int64_t k_uptime_delta(int64_t *reftime)
 	return delta;
 }
 
-/**
- * @brief Get elapsed time (32-bit version).
- *
- * This routine computes the elapsed time between the current system uptime
- * and an earlier reference time, in milliseconds.
- *
- * This is a wrapper around k_uptime_delta().
- *
- * @param reftime Pointer to a reference time, which is updated to the current
- *                uptime upon return.
- *
- * @return Elapsed time.
- *
- * @deprecated in 2.3 release, replace with k_uptime_delta()
- */
-__deprecated static inline uint32_t k_uptime_delta_32(int64_t *reftime)
-{
-	return (uint32_t)k_uptime_delta(reftime);
-}
-
 /**
  * @brief Read the hardware clock.
  *
@@ -2210,8 +2154,6 @@ struct k_queue {
 	_OBJECT_TRACING_INIT \
 	}
 
-#define K_QUEUE_INITIALIZER __DEPRECATED_MACRO Z_QUEUE_INITIALIZER
-
 extern void *z_queue_node_peek(sys_sfnode_t *node, bool needs_free);
 
 /**
@@ -2596,8 +2538,6 @@ struct k_fifo {
 	._queue = Z_QUEUE_INITIALIZER(obj._queue) \
 	}
 
-#define K_FIFO_INITIALIZER __DEPRECATED_MACRO Z_FIFO_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -2801,8 +2741,6 @@ struct k_lifo {
 	._queue = Z_QUEUE_INITIALIZER(obj._queue) \
 	}
 
-#define K_LIFO_INITIALIZER __DEPRECATED_MACRO Z_LIFO_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -2920,8 +2858,6 @@ struct k_stack {
 	_OBJECT_TRACING_INIT \
 	}
 
-#define K_STACK_INITIALIZER __DEPRECATED_MACRO Z_STACK_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -3109,8 +3045,6 @@ extern struct k_work_q k_sys_work_q;
 	.flags = { 0 } \
 	}
 
-#define K_WORK_INITIALIZER __DEPRECATED_MACRO Z_WORK_INITIALIZER
-
 /**
  * @brief Initialize a statically-defined work item.
  *
@@ -3623,8 +3557,6 @@ struct k_mutex {
 	_OBJECT_TRACING_INIT \
 	}
 
-#define K_MUTEX_INITIALIZER __DEPRECATED_MACRO Z_MUTEX_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -3729,8 +3661,6 @@ struct k_sem {
 	_OBJECT_TRACING_INIT \
 	}
 
-#define K_SEM_INITIALIZER __DEPRECATED_MACRO Z_SEM_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -3897,7 +3827,7 @@ struct k_msgq {
 	.used_msgs = 0, \
 	_OBJECT_TRACING_INIT \
 	}
-#define K_MSGQ_INITIALIZER __DEPRECATED_MACRO Z_MSGQ_INITIALIZER
+
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -4179,8 +4109,6 @@ struct k_mbox {
 	_OBJECT_TRACING_INIT \
 	}
 
-#define K_MBOX_INITIALIZER __DEPRECATED_MACRO Z_MBOX_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -4369,8 +4297,6 @@ struct k_pipe {
 	.flags = 0                                                  \
 	}
 
-#define K_PIPE_INITIALIZER __DEPRECATED_MACRO Z_PIPE_INITIALIZER
-
 /**
  * INTERNAL_HIDDEN @endcond
  */
@@ -4551,8 +4477,6 @@ struct k_mem_slab {
 	_OBJECT_TRACING_INIT \
 	}
 
-#define K_MEM_SLAB_INITIALIZER __DEPRECATED_MACRO Z_MEM_SLAB_INITIALIZER
-
 
 /**
  * INTERNAL_HIDDEN @endcond