diff --git a/drivers/mbox/mbox_nrf_vevif_task_rx.c b/drivers/mbox/mbox_nrf_vevif_task_rx.c
index 8a4d81e0e6e..a489d4d3717 100644
--- a/drivers/mbox/mbox_nrf_vevif_task_rx.c
+++ b/drivers/mbox/mbox_nrf_vevif_task_rx.c
@@ -116,9 +116,25 @@ static const struct mbox_driver_api vevif_task_rx_driver_api = {
 	.set_enabled = vevif_task_rx_set_enabled,
 };
 
+#if defined(CONFIG_GEN_SW_ISR_TABLE)
 #define VEVIF_IRQ_CONNECT(idx, _)                                                                  \
 	IRQ_CONNECT(DT_INST_IRQ_BY_IDX(0, idx, irq), DT_INST_IRQ_BY_IDX(0, idx, priority),         \
 		    vevif_task_rx_isr, &vevif_irqs[idx], 0)
+#else
+
+#define VEVIF_IRQ_FUN(idx, _)                 \
+ISR_DIRECT_DECLARE(vevif_task_##idx##_rx_isr) \
+{                                             \
+	vevif_task_rx_isr(&vevif_irqs[idx]);  \
+	return 1;                             \
+}
+
+LISTIFY(DT_NUM_IRQS(DT_DRV_INST(0)), VEVIF_IRQ_FUN, ())
+
+#define VEVIF_IRQ_CONNECT(idx, _)                                                                 \
+	IRQ_DIRECT_CONNECT(DT_INST_IRQ_BY_IDX(0, idx, irq), DT_INST_IRQ_BY_IDX(0, idx, priority), \
+		    vevif_task_##idx##_rx_isr, 0)
+#endif
 
 static int vevif_task_rx_init(const struct device *dev)
 {