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Audio should work. The problem should be the codec for mp3 or other non-free media formats. See Support mp3 and H264 in video and audio tag
2 extra DLL files from DirectX are needed, or your GFX card/driver is on Chromium's black list. See https://github.com/rogerwang/node-webkit/issues/185
Sometimes the css doesn't display correctly, such as -webkit-transform:translateZ(-1000px);. Maybe it's the problem with the WebGL.
Maybe node-webkit doesn't work on your computer with the error.
nw: error while loading shared libraries: libudev.so.0: cannot open shared object file: No such file or directory
See issues #136, #770, and the temporary solution The solution of lacking libudev.so.0