new term request: axochord #574

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ANiknejad opened this Issue Sep 19, 2014 · 3 comments

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Hi Chris,

from very recent and exciting literature:
http://www.ncbi.nlm.nih.gov/pubmed/25214631

"We next examined whether an axochord is also present in other annelids, lophotrochozoans, or protostomes (Fig. 1C). Phalloidin stainings had revealed ventral midline muscles in almost all annelid families (table S3), yet in some cases only pairs of ventral muscles had been reported...
An ancestral state reconstruction based on our data and on a survey of bilaterian musculature (table S3) favored the presence of an axochord in protostome ancestors (fig. S14). "

Thank you

Anne

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cmungall commented Sep 19, 2014

This is very cool. We should take this opportunity to unify the developmental model for notochord. Currently we have:

nt

(hmm, ectoderm doesn't seem right... I think this was from an earlier version of EHDAA2)

For the axochord, I think we need at least two classes:

  1. axochord, a muscle, which develops from:
  2. the axochord precursor, a population of mesodermal cells

but this doesn't seem to do full justice by itself, need to represent the cells and matrix somehow?

Owner

cmungall commented Sep 19, 2014

btw, if there is interest, we could divest annelid terms from core, and make this a separate owl module others can freely edit...

Help here for defining the classes
http://www.kalliopimonoyios.com/illustrations/EMBLAxochord.html
http://www.hhmi.ucla.edu/derobertis/EDR_MS/Evo-Devo_page/EVO-DEVO.html

Tentatives definitions for 1. and 2. above:

  1. the ventral midline of annelid embryos has a medial muscle called the axochord
  2. contractile mesodermal midline cells

I need the term 'axochord' in Uberon, thanks!

cmungall closed this in c1e617b Apr 24, 2015

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