Open Systems Pharmacology

Repositories

• OSPSuite.Core

  Core functionalities of the Open Systems Pharmacology Suite

  suite-components
  C# 6 2 59 2 Updated Apr 12, 2021

• PK-Sim

  PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling

  suite-components pk-sim
  C# 34 53 326 1 Updated Apr 12, 2021

• docs

  Open Systems Pharmacology - Live Documentation
  JavaScript 17 4 50 1 Updated Apr 12, 2021

• OSPSuite.ReportingEngine

  R implementation of the reporting engine
  R 5 1 46 0 Updated Apr 10, 2021

• Irinotecan-Model

  Whole-body PBPK model of Irinotecan (CPT-11) & SN-38 determining tumor tissue kinetics of both parent drug & active metabolite.

  mobi pbpk pk-sim
  0 0 0 0 Updated Apr 8, 2021

• QualificationRunner

  Qualification runner in charge of managing a qualification workflow

  suite-components
  C# 1 0 10 0 Updated Apr 8, 2021

• OSPSuite-R

  R package for the OSPSuite
  R 4 0 41 0 Updated Apr 6, 2021

• FDA-OSP-training-April-2021

  osp-workshop
  0 0 0 0 Updated Apr 6, 2021

• MoBi

  MoBi® is a software tool for multiscale physiological modeling and simulation

  mobi suite-components
  C# 6 14 150 0 Updated Apr 2, 2021

• InstallationValidator

  Installation Validation Tool for the Open Systems Pharmacology Suite

  suite-components
  C# 2 1 11 0 Updated Mar 30, 2021

• OSMOSES

  Open-Source MOdeling framework for automated quality control and management of complex life Science systEms modelS (OSMOSES)
  0 0 26 0 Updated Mar 30, 2021

• Carbamazepine-Efavirenz-DDI

  Modeling of published clinical Carbamazepine-Efavirenz DDI studies for model evaluation

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 30, 2021

• Erythromycin-Carbamazepine-DDI

  Modeling of published clinical Erythromycin-Carbamazepine DDI studies for model evaluation

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 30, 2021

• Carbamazepine-Bupropion-DDI

  Modeling of published clinical Carbamazepine-Bupropion-DDI studies for model evaluation

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 30, 2021

• Carbamazepine-Alprazolam-DDI

  Modeling of published clinical Carbamazepine-Alprazolam-DDI studies for model evaluation

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 30, 2021

• Carbamazepine-Model

  PBPK model of carbamazepine as CYP3A4 and CYP2B6 substrate and inducer

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 30, 2021

• build-scripts

  Collection of rake tasks used during build

  suite-components
  Ruby 3 0 0 0 Updated Mar 29, 2021

• PharMetrX-Workshop-April-2021

  Training materials for the PharMetrX OSP PBPK workshop, online, April 2021
  0 0 0 0 Updated Mar 29, 2021

• Efavirenz-Model

  Whole-body PBPK model of efavirenz as CYP3A4 perpetrator drug

  osp-model
  MATLAB 3 0 0 1 Updated Mar 29, 2021

• Database-for-observed-data

  Forked from NinaHanke/Database-for-observed-data

  Database for published pharmacokinetic data
  R 5 0 3 0 Updated Mar 26, 2021

• Fluvoxamine-Model

  Whole-body PBPK model of fluvoxamine as CYP1A2 and CYP3A4 DDI perpetrator drug

  ddi pbpk osp-model pk-sim
  2 0 3 0 Updated Mar 26, 2021

• Bupropion-Model

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 26, 2021

• Fluvoxamine-Voriconazole-Bupropion-DDI

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 26, 2021

• Rifampicin-Bupropion-DDI

  ddi pbpk osp-model pk-sim
  0 0 0 0 Updated Mar 26, 2021

• TLF-Library

  TLF Library implementation in R
  R 2 0 56 0 Updated Mar 18, 2021

• Qualification-DDI-CYP1A2

  Qualification of OSP platform for CYP1A2-mediated DDI

  osp-qualification
  MATLAB 0 0 0 0 Updated Mar 16, 2021

• Aripiprazole-Model

  osp-model
  1 0 0 0 Updated Mar 10, 2021

• Quetiapine-Model

  osp-model
  2 0 0 0 Updated Mar 9, 2021

• OSPSuite-Epics

  Repository used to define epics for our releases
  0 0 6 0 Updated Mar 4, 2021

• OSPSuite.Dimensions

  List of dimensions supported by the Open Systems Pharmacology Suite

  suite-components
  2 0 2 0 Updated Mar 3, 2021