diff --git a/CHANGELOG.md b/CHANGELOG.md
index 28e8a85c26..ab9b88a4ed 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -51,6 +51,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
   ([#2461](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/2461))
 - Remove SDK dependency from opentelemetry-instrumentation-grpc
   ([#2474](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/2474))
+- `opentelemetry-instrumentation-asyncio` Check for __name__ attribute in the coroutine
+  ([#2521](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/2521))
 
 ## Version 1.24.0/0.45b0 (2024-03-28)
 
diff --git a/instrumentation/opentelemetry-instrumentation-asyncio/src/opentelemetry/instrumentation/asyncio/__init__.py b/instrumentation/opentelemetry-instrumentation-asyncio/src/opentelemetry/instrumentation/asyncio/__init__.py
index 72aa5fd2aa..aea7c585fc 100644
--- a/instrumentation/opentelemetry-instrumentation-asyncio/src/opentelemetry/instrumentation/asyncio/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-asyncio/src/opentelemetry/instrumentation/asyncio/__init__.py
@@ -254,7 +254,9 @@ def trace_item(self, coro_or_future):
         # Task is already traced, return it
         if isinstance(coro_or_future, asyncio.Task):
             return coro_or_future
-        if asyncio.iscoroutine(coro_or_future):
+        if asyncio.iscoroutine(coro_or_future) and hasattr(
+            coro_or_future, "__name__"
+        ):
             return self.trace_coroutine(coro_or_future)
         if futures.isfuture(coro_or_future):
             return self.trace_future(coro_or_future)
diff --git a/instrumentation/opentelemetry-instrumentation-asyncio/tests/test_asyncio_anext.py b/instrumentation/opentelemetry-instrumentation-asyncio/tests/test_asyncio_anext.py
new file mode 100644
index 0000000000..9ce3fc4b33
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-asyncio/tests/test_asyncio_anext.py
@@ -0,0 +1,56 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+import asyncio
+from unittest.mock import patch
+
+# pylint: disable=no-name-in-module
+from opentelemetry.instrumentation.asyncio import AsyncioInstrumentor
+from opentelemetry.instrumentation.asyncio.environment_variables import (
+    OTEL_PYTHON_ASYNCIO_COROUTINE_NAMES_TO_TRACE,
+)
+from opentelemetry.test.test_base import TestBase
+from opentelemetry.trace import get_tracer
+
+
+class TestAsyncioAnext(TestBase):
+    @patch.dict(
+        "os.environ",
+        {OTEL_PYTHON_ASYNCIO_COROUTINE_NAMES_TO_TRACE: "async_func"},
+    )
+    def setUp(self):
+        super().setUp()
+        AsyncioInstrumentor().instrument()
+        self._tracer = get_tracer(
+            __name__,
+        )
+
+    def tearDown(self):
+        super().tearDown()
+        AsyncioInstrumentor().uninstrument()
+
+    # Asyncio anext() does not have __name__ attribute, which is used to determine if the coroutine should be traced.
+    # This test is to ensure that the instrumentation does not break when the coroutine does not have __name__ attribute.
+    def test_asyncio_anext(self):
+        async def main():
+            async def async_gen():
+                for it in range(2):
+                    yield it
+
+            async_gen_instance = async_gen()
+            agen = anext(async_gen_instance)
+            await asyncio.create_task(agen)
+
+        asyncio.run(main())
+        spans = self.memory_exporter.get_finished_spans()
+        self.assertEqual(len(spans), 0)