diff --git a/instrumentation/opentelemetry-instrumentation-botocore/CHANGELOG.md b/instrumentation/opentelemetry-instrumentation-botocore/CHANGELOG.md
index 4894f1b204..ea05e4d721 100644
--- a/instrumentation/opentelemetry-instrumentation-botocore/CHANGELOG.md
+++ b/instrumentation/opentelemetry-instrumentation-botocore/CHANGELOG.md
@@ -3,6 +3,8 @@
 ## Unreleased
 - Add propagator injection for botocore calls
   ([#181](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/181))
+- Make botocore instrumentation check if instrumentation has been suppressed
+  ([#182](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/182))
 
 ## Version 0.13b0
 
diff --git a/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py b/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py
index a29e56a779..1bbc6af13b 100644
--- a/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-botocore/src/opentelemetry/instrumentation/botocore/__init__.py
@@ -56,6 +56,7 @@
 from botocore.client import BaseClient
 from wrapt import ObjectProxy, wrap_function_wrapper
 
+from opentelemetry import context as context_api
 from opentelemetry import propagators
 from opentelemetry.instrumentation.botocore.version import __version__
 from opentelemetry.instrumentation.instrumentor import BaseInstrumentor
@@ -104,6 +105,8 @@ def _uninstrument(self, **kwargs):
         unwrap(BaseClient, "_make_api_call")
 
     def _patched_api_call(self, original_func, instance, args, kwargs):
+        if context_api.get_value("suppress_instrumentation"):
+            return original_func(*args, **kwargs)
 
         endpoint_name = deep_getattr(instance, "_endpoint._endpoint_prefix")
 
diff --git a/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py b/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py
index 3d5eb4db9d..8c1cb4c0c1 100644
--- a/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py
+++ b/instrumentation/opentelemetry-instrumentation-botocore/tests/test_botocore_instrumentation.py
@@ -23,9 +23,11 @@
     mock_lambda,
     mock_s3,
     mock_sqs,
+    mock_xray,
 )
 
 from opentelemetry import propagators
+from opentelemetry.context import attach, detach, set_value
 from opentelemetry.instrumentation.botocore import BotocoreInstrumentor
 from opentelemetry.sdk.resources import Resource
 from opentelemetry.test.mock_textmap import MockTextMapPropagator
@@ -330,3 +332,16 @@ def check_headers(**kwargs):
 
         finally:
             propagators.set_global_textmap(previous_propagator)
+
+    @mock_xray
+    def test_suppress_instrumentation_xray_client(self):
+        xray_client = self.session.create_client(
+            "xray", region_name="us-east-1"
+        )
+        token = attach(set_value("suppress_instrumentation", True))
+        xray_client.put_trace_segments(TraceSegmentDocuments=["str1"])
+        xray_client.put_trace_segments(TraceSegmentDocuments=["str2"])
+        detach(token)
+
+        spans = self.memory_exporter.get_finished_spans()
+        self.assertEqual(0, len(spans))