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S-gene target failure (SGTF) and case fatality risk (CFR)

This is a study of the CFR of the SARS-CoV-2 variant of concern B.1.1.7 (VOC) compared to the non-VOC. SGTF is used as a proxy for identifying the VOC.

This is the code and configuration for our analysis

About the OpenSAFELY framework

The OpenSAFELY framework is a new secure analytics platform for electronic health records research in the NHS.

Instead of requesting access for slices of patient data and transporting them elsewhere for analysis, the framework supports developing analytics against dummy data, and then running against the real data within the same infrastructure that the data is stored. Read more at

The framework is under fast, active development to support rapid analytics relating to COVID19; we're currently seeking funding to make it easier for outside collaborators to work with our system. You can read our current roadmap here.


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