diff --git a/Makefile b/Makefile
index a29cf39c2..4343caf7e 100644
--- a/Makefile
+++ b/Makefile
@@ -184,6 +184,9 @@ test-e2e-upgrade: manifests
 
 test-e2e: test-e2e-operator test-e2e-handler
 
+test-e2e-ocp: 
+	./hack/ocp-e2e-tests.sh
+
 cluster-up:
 	./cluster/up.sh
 
diff --git a/hack/ocp-e2e-tests.sh b/hack/ocp-e2e-tests.sh
index b052ee849..9c0fb8848 100755
--- a/hack/ocp-e2e-tests.sh
+++ b/hack/ocp-e2e-tests.sh
@@ -19,6 +19,22 @@ export PRIMARY_NIC=enp2s0
 export FIRST_SECONDARY_NIC=enp3s0
 export SECOND_SECONDARY_NIC=enp4s0
 
+if oc get ns openshift-ovn-kubernetes &> /dev/null; then
+    # We are using OVNKubernetes -> use enp1s0 as primary nic
+    export PRIMARY_NIC=enp1s0
+fi
+
+# Apply machine configs and wait until machine config pools got updated
+old_mcp_generation=$(oc get mcp master -o jsonpath={.metadata.generation})
+if oc create -f test/e2e/machineconfigs.yaml; then
+    # If MCs could be created, wait until the MCP are aware of new machine configs
+    while [ "$old_mcp_generation" -eq "$(oc get mcp master -o jsonpath={.metadata.generation})" ]; do 
+        echo "waiting for MCP update to start..."; 
+        sleep 1; 
+    done
+fi
+while ! oc wait mcp --all --for=condition=Updated --timeout -1s; do sleep 1; done
+
 make cluster-sync-operator
 # Will fail on subsequent runs, this is fine.
 oc create -f build/_output/manifests/scc.yaml || :
diff --git a/test/e2e/machineconfigs.yaml b/test/e2e/machineconfigs.yaml
new file mode 100644
index 000000000..5d14309d4
--- /dev/null
+++ b/test/e2e/machineconfigs.yaml
@@ -0,0 +1,52 @@
+apiVersion: machineconfiguration.openshift.io/v1
+kind: MachineConfig
+metadata:
+  labels:
+    machineconfiguration.openshift.io/role: master
+  name: 10-nmstate-hack-master
+spec:
+  config:
+    ignition:
+      version: 3.2.0
+    systemd:
+      units:
+      - contents: |
+          [Unit]
+          Description=NMState e2e hack
+          Wants=crio.service
+          Before=kubelet.service
+          After=crio.service
+          [Service]
+          Type=oneshot
+          ExecStart=/bin/bash -c "for i in $(nmcli --fields NAME,UUID -t con show | grep 'Wired Connection' | awk -F : '{print $2}'); do nmcli con modify $i match.interface-name '!enp3s0, !enp4s0'; done"
+          [Install]
+          WantedBy=multi-user.target
+        enabled: true
+        name: nmstate-hack.service
+
+---
+apiVersion: machineconfiguration.openshift.io/v1
+kind: MachineConfig
+metadata:
+  labels:
+    machineconfiguration.openshift.io/role: worker
+  name: 10-nmstate-hack-worker
+spec:
+  config:
+    ignition:
+      version: 3.2.0
+    systemd:
+      units:
+      - contents: |
+          [Unit]
+          Description=NMState e2e hack
+          Wants=crio.service
+          Before=kubelet.service
+          After=crio.service
+          [Service]
+          Type=oneshot
+          ExecStart=/bin/bash -c "for i in $(nmcli --fields NAME,UUID -t con show | grep 'Wired Connection' | awk -F : '{print $2}'); do nmcli con modify $i match.interface-name '!enp3s0, !enp4s0'; done"
+          [Install]
+          WantedBy=multi-user.target
+        enabled: true
+        name: nmstate-hack.service