diff --git a/packages/oui-select/README.md b/packages/oui-select/README.md
index 23eb4613..d6b4e6a7 100644
--- a/packages/oui-select/README.md
+++ b/packages/oui-select/README.md
@@ -68,6 +68,24 @@
 </oui-select>
 ```
 
+### Disabled Items
+
+```html:preview
+<oui-select name="country"
+    model="$ctrl.country"
+    data-title="Select a country"
+    placeholder="Select a country..."
+    items="$ctrl.countries"
+    disable-items="$ctrl.disableItems($item)"
+    required
+    match="name"
+    data-align="start">
+    <span ng-bind="$item.name"></span>
+</oui-select>
+```
+
+**Note**: For each `$item` in `items` array, `disable-item` will be called with current `$item` as an argument. If it returns true, `$item` will be disabled. 
+
 ### On Change
 
 **Note**: Model will not be refreshed until the `on-change` callback hasn't returned. If you want to access the new model inside the `on-change` callback you need to use the `modelValue` variable as below.
@@ -110,6 +128,7 @@
 | `placeholder` | string    | @?        | yes               | n/a               | n/a       | placeholder displayed when model is undefined
 | `match`       | string    | @?        | no                | n/a               | n/a       | property of item to show as selected item
 | `items`       | array     | <         | no                | n/a               | n/a       | array used to populate the list
+| `disable-items`| function | &         | no                | n/a               | n/a       | predicate to determine items to disable
 | `required`    | boolean   | <?        | no                | `true`, `false`   | `false`   | define if the field is required
 | `disabled`    | boolean   | <?        | no                | `true`, `false`   | `false`   | define if the field is disabled
 | `group-by`    | function  | <?        | no                | n/a               | n/a       | function taking an item as parameter and returning the group name as as string
diff --git a/packages/oui-select/src/index.spec.js b/packages/oui-select/src/index.spec.js
index 338fbbbd..8acbe5cf 100644
--- a/packages/oui-select/src/index.spec.js
+++ b/packages/oui-select/src/index.spec.js
@@ -289,5 +289,59 @@ describe("ouiSelect", () => {
                 expect(onChange).toHaveBeenCalledWith(data[index2]);
             });
         });
+
+        describe("Disable options", () => {
+            it("should disable corresponding items", () => {
+                const disableCountry = (item) => item.name === data[3].name;
+                const element = TestUtils.compileTemplate(`
+                    <oui-select name="country"
+                                model="$ctrl.country"
+                                title="Select a country"
+                                placeholder="Select a country..."
+                                items="$ctrl.countries"
+                                disable-items="$ctrl.disableCountry($item)"
+                                match="name">
+                        <span ng-bind="$item.name"></span>
+                    </oui-select>`, {
+                    countries: data,
+                    disableCountry
+                });
+
+                $timeout.flush();
+
+                // Trigger click to update the options with corresponding dynamic attributes
+                getDropdownButton(element).click();
+                expect(angular.element(getDropdownItem(element, 3)).prop("disabled")).toBeTruthy();
+            });
+
+            it("should update item", () => {
+                const countries = data.concat({ name: "Imaginary country", code: "IC" });
+                const disableCountry = (item) => item.code === "";
+                const element = TestUtils.compileTemplate(`
+                    <oui-select name="country"
+                                model="$ctrl.country"
+                                title="Select a country"
+                                placeholder="Select a country..."
+                                items="$ctrl.countries"
+                                disable-items="$ctrl.disableCountry($item)"
+                                match="name">
+                        <span ng-bind="$item.name"></span>
+                    </oui-select>`, {
+                    countries,
+                    disableCountry
+                });
+
+                $timeout.flush();
+
+                // Trigger click to update the options with corresponding dynamic attributes
+                getDropdownButton(element).click();
+                expect(angular.element(getDropdownItem(element, data.length - 1)).prop("disabled")).toBeFalsy();
+
+                element.scope().$ctrl.countries[data.length - 1].code = "";
+                $timeout.flush();
+
+                expect(angular.element(getDropdownItem(element, data.length - 1)).prop("disabled")).toBeTruthy();
+            });
+        });
     });
 });
diff --git a/packages/oui-select/src/select.directive.js b/packages/oui-select/src/select.directive.js
index d2233f54..45a76cd9 100644
--- a/packages/oui-select/src/select.directive.js
+++ b/packages/oui-select/src/select.directive.js
@@ -17,6 +17,7 @@ export default () => ({
         title: "@?",
         placeholder: "@?",
         items: "<",
+        disableItems: "&",
         match: "@?",
         groupBy: "<?",
         align: "@?",
diff --git a/packages/oui-select/src/select.html b/packages/oui-select/src/select.html
index 3ad6885c..e428e973 100644
--- a/packages/oui-select/src/select.html
+++ b/packages/oui-select/src/select.html
@@ -9,5 +9,5 @@
         on-focus="$ctrl.onUiSelectFocus()"
         on-select="$ctrl.onChange({ modelValue: $model })">
     <oui-ui-select-match placeholder="{{::$ctrl.placeholder}}"></oui-ui-select-match>
-    <oui-ui-select-choices repeat="$item in $ctrl.items track by $index"></oui-ui-select-choices>
+    <oui-ui-select-choices repeat="$item in $ctrl.items track by $index" ui-disable-choice="$ctrl.disableItems({ $item: $item })"></oui-ui-select-choices>
 </oui-ui-select>
diff --git a/packages/oui-select/src/templates/choices.html b/packages/oui-select/src/templates/choices.html
index 39ca7a5f..80888d58 100644
--- a/packages/oui-select/src/templates/choices.html
+++ b/packages/oui-select/src/templates/choices.html
@@ -5,10 +5,11 @@
             ng-attr-id="ui-select-choices-row-{{ $select.generatedId }}-{{$index}}"
             class="ui-select-choices-row oui-dropdown-option"
             ng-class="{
-                active: $select.isActive(this),
+                active: $select.isActive(this) && !$select.isDisabled(this),
                 selected: $select.isSelected(this),
                 disabled: $select.isDisabled(this)
             }"
+            ng-disabled="$select.isDisabled(this)"
             role="option"
             type="button">
             <span class="ui-select-choices-row-inner" ng-class="{ 'ui-select-choices-row-inner_grouped': $select.isGrouped }">