diff --git a/pandas/core/common.py b/pandas/core/common.py
index 30f6b66a2b7d3..71d767a57bccb 100644
--- a/pandas/core/common.py
+++ b/pandas/core/common.py
@@ -8,13 +8,6 @@
 
 import itertools
 
-try:
-    next
-except NameError:  # pragma: no cover
-    # Python < 2.6
-    def next(x):
-        return x.next()
-
 from numpy.lib.format import read_array, write_array
 import numpy as np
 
diff --git a/pandas/core/frame.py b/pandas/core/frame.py
index f7f296e822e15..44b31926f4e15 100644
--- a/pandas/core/frame.py
+++ b/pandas/core/frame.py
@@ -1,5 +1,3 @@
-from __future__ import with_statement
-
 """
 DataFrame
 ---------
diff --git a/pandas/io/parsers.py b/pandas/io/parsers.py
index 52c8c4aa65a13..a5fc7ebeed101 100644
--- a/pandas/io/parsers.py
+++ b/pandas/io/parsers.py
@@ -7,13 +7,6 @@
 from urlparse import urlparse
 import csv
 
-try:
-    next
-except NameError:  # pragma: no cover
-    # Python < 2.6
-    def next(x):
-        return x.next()
-
 import numpy as np
 
 from pandas.core.index import Index, MultiIndex
diff --git a/pandas/io/tests/test_pytables.py b/pandas/io/tests/test_pytables.py
index 9442f274a7810..afd05610e3427 100644
--- a/pandas/io/tests/test_pytables.py
+++ b/pandas/io/tests/test_pytables.py
@@ -1,5 +1,3 @@
-from __future__ import with_statement
-
 import nose
 import unittest
 import os
@@ -723,4 +721,3 @@ def _test_sort(obj):
     import nose
     nose.runmodule(argv=[__file__,'-vvs','-x','--pdb', '--pdb-failure'],
                    exit=False)
-
diff --git a/pandas/tests/test_common.py b/pandas/tests/test_common.py
index 44c40b6930784..661c3a2a3edd8 100644
--- a/pandas/tests/test_common.py
+++ b/pandas/tests/test_common.py
@@ -1,4 +1,3 @@
-from __future__ import with_statement
 from datetime import datetime
 import sys
 
diff --git a/pandas/tests/test_graphics.py b/pandas/tests/test_graphics.py
index 708f8143de3d5..05f9e51150850 100644
--- a/pandas/tests/test_graphics.py
+++ b/pandas/tests/test_graphics.py
@@ -1,5 +1,3 @@
-from __future__ import with_statement
-
 import nose
 import os
 import string
@@ -460,9 +458,9 @@ def test_parallel_coordinates(self):
         path = os.path.join(curpath(), 'data/iris.csv')
         df = read_csv(path)
         _check_plot_works(parallel_coordinates, df, 'Name')
-        _check_plot_works(parallel_coordinates, df, 'Name', 
+        _check_plot_works(parallel_coordinates, df, 'Name',
                           colors=('#556270', '#4ECDC4', '#C7F464'))
-        _check_plot_works(parallel_coordinates, df, 'Name', 
+        _check_plot_works(parallel_coordinates, df, 'Name',
                           colors=['dodgerblue', 'aquamarine', 'seagreen'])
 
     @slow
diff --git a/pandas/tseries/tests/test_timeseries.py b/pandas/tseries/tests/test_timeseries.py
index 86feb68052f67..6cec53eff382f 100644
--- a/pandas/tseries/tests/test_timeseries.py
+++ b/pandas/tseries/tests/test_timeseries.py
@@ -1,5 +1,4 @@
 # pylint: disable-msg=E1101,W0612
-from __future__ import with_statement # for Python 2.5
 import pandas.util.compat as itertools
 from datetime import datetime, time, timedelta
 import sys
diff --git a/pandas/tseries/tests/test_timezones.py b/pandas/tseries/tests/test_timezones.py
index 688e4945b6eb3..5da018b54ad4a 100644
--- a/pandas/tseries/tests/test_timezones.py
+++ b/pandas/tseries/tests/test_timezones.py
@@ -1,5 +1,4 @@
 # pylint: disable-msg=E1101,W0612
-from __future__ import with_statement # for Python 2.5
 from datetime import datetime, time, timedelta, tzinfo
 import sys
 import os
diff --git a/tox.ini b/tox.ini
index 7d09b3aa887e1..9f8e1af8ae924 100644
--- a/tox.ini
+++ b/tox.ini
@@ -4,7 +4,7 @@
 # and then run "tox" from this directory.
 
 [tox]
-envlist = py25, py26, py27, py31, py32
+envlist = py26, py27, py31, py32
 
 [testenv]
 deps =
@@ -35,15 +35,6 @@ commands =
     # tox should provide a preinstall-commands hook.
     pip uninstall pandas -qy
 
-
-[testenv:py25]
-deps =
-    cython
-    numpy >= 1.6.1
-    nose
-    pytz
-    simplejson
-
 [testenv:py26]
 
 [testenv:py27]
diff --git a/tox_prll.ini b/tox_prll.ini
index 85856db064ca3..70edffac717a2 100644
--- a/tox_prll.ini
+++ b/tox_prll.ini
@@ -4,7 +4,7 @@
 # and then run "tox" from this directory.
 
 [tox]
-envlist = py25, py26, py27, py31, py32
+envlist = py26, py27, py31, py32
 sdistsrc = {env:DISTFILE}
 
 [testenv]
@@ -36,15 +36,6 @@ commands =
     # tox should provide a preinstall-commands hook.
     pip uninstall pandas -qy
 
-
-[testenv:py25]
-deps =
-    cython
-    numpy >= 1.6.1
-    nose
-    pytz
-    simplejson
-
 [testenv:py26]
 
 [testenv:py27]