diff --git a/doc/source/whatsnew/v2.2.1.rst b/doc/source/whatsnew/v2.2.1.rst
index e1da0af59b3b8..792f98f1366dd 100644
--- a/doc/source/whatsnew/v2.2.1.rst
+++ b/doc/source/whatsnew/v2.2.1.rst
@@ -40,6 +40,7 @@ Fixed regressions
 - Fixed regression in :meth:`Index.join` raising ``TypeError`` when joining an empty index to a non-empty index containing mixed dtype values (:issue:`57048`)
 - Fixed regression in :meth:`Series.pct_change` raising a ``ValueError`` for an empty :class:`Series` (:issue:`57056`)
 - Fixed regression in :meth:`Series.to_numpy` when dtype is given as float and the data contains NaNs (:issue:`57121`)
+- Fixed regression where dividing a :class:`tseries.offsets.Tick` by a value greater than its :attr:`tseries.offsets.Tick.n` would incorrectly return 0 instead of changing to a higher resolution (:issue:`57264`)
 
 .. ---------------------------------------------------------------------------
 .. _whatsnew_221.bug_fixes:
diff --git a/pandas/_libs/tslibs/timedeltas.pyx b/pandas/_libs/tslibs/timedeltas.pyx
index f6c69cf6d3875..9e068e952a94c 100644
--- a/pandas/_libs/tslibs/timedeltas.pyx
+++ b/pandas/_libs/tslibs/timedeltas.pyx
@@ -60,6 +60,7 @@ from pandas._libs.tslibs.np_datetime cimport (
     cmp_dtstructs,
     cmp_scalar,
     convert_reso,
+    get_conversion_factor,
     get_datetime64_unit,
     get_unit_from_dtype,
     import_pandas_datetime,
@@ -965,6 +966,7 @@ cdef _timedelta_from_value_and_reso(cls, int64_t value, NPY_DATETIMEUNIT reso):
     #  many cases would fall outside of the pytimedelta implementation bounds.
     #  We pass 0 instead, and override seconds, microseconds, days.
     #  In principle we could pass 0 for ns and us too.
+
     if reso == NPY_FR_ns:
         td_base = _Timedelta.__new__(cls, microseconds=int(value) // 1000)
     elif reso == NPY_DATETIMEUNIT.NPY_FR_us:
@@ -2047,6 +2049,9 @@ class Timedelta(_Timedelta):
     __rmul__ = __mul__
 
     def __truediv__(self, other):
+        cdef:
+            NPY_DATETIMEUNIT curr_unit, next_unit
+            int64_t curr_value
         if _should_cast_to_timedelta(other):
             # We interpret NaT as timedelta64("NaT")
             other = Timedelta(other)
@@ -2066,8 +2071,21 @@ class Timedelta(_Timedelta):
                 other = int(other)
             if isinstance(other, cnp.floating):
                 other = float(other)
+
+            # If we have a non-nano timedelta and
+            # self._value < other, we would get 0 as a result,
+            # which is not correct.
+            # We need to try going to a higher resolution to fix this
+            curr_value = self._value
+            curr_unit = self._creso
+            while curr_value < other and curr_unit < NPY_FR_ns:
+                next_unit = <NPY_DATETIMEUNIT>(<int64_t>curr_unit + 1)
+                cf = get_conversion_factor(curr_unit, next_unit)
+                curr_value *= cf
+                curr_unit = next_unit
+
             return Timedelta._from_value_and_reso(
-                <int64_t>(self._value/ other), self._creso
+                <int64_t>(curr_value / other), curr_unit
             )
 
         elif is_array(other):
diff --git a/pandas/tests/tseries/offsets/test_ticks.py b/pandas/tests/tseries/offsets/test_ticks.py
index 399b7038d3426..085e22c315d23 100644
--- a/pandas/tests/tseries/offsets/test_ticks.py
+++ b/pandas/tests/tseries/offsets/test_ticks.py
@@ -266,6 +266,11 @@ def test_tick_division(cls):
         result = off / 1000
         assert isinstance(result, offsets.Tick)
         assert not isinstance(result, cls)
+        # GH57264
+        # Test that roundtripping works
+        # to ensure that the timedelta division isn't giving something wrong
+        # (e.g. 0)
+        assert result * 1000 == off
         assert result._as_pd_timedelta == off._as_pd_timedelta / 1000
 
     if cls._nanos_inc < Timedelta(seconds=1)._value: