diff --git a/scriptmodules/emulators/mupen64plus.sh b/scriptmodules/emulators/mupen64plus.sh
index 641a618628..8a81a26a6d 100644
--- a/scriptmodules/emulators/mupen64plus.sh
+++ b/scriptmodules/emulators/mupen64plus.sh
@@ -52,7 +52,10 @@ function sources_mupen64plus() {
         gitPullOrClone "$dir" https://github.com/${repo[0]}/mupen64plus-${repo[1]} ${repo[2]}
     done
     gitPullOrClone "$md_build/GLideN64" https://github.com/gonetz/GLideN64.git
-    
+
+    # temporary workaround for https://github.com/gonetz/GLideN64/issues/1665
+    isPlatform "rpi" && applyPatch "$md_data/rpi-yuv.diff"
+
     local config_version=$(grep -oP '(?<=CONFIG_VERSION_CURRENT ).+?(?=U)' GLideN64/src/Config.h)
     echo "$config_version" > "$md_build/GLideN64_config_version.ini"
 }
diff --git a/scriptmodules/emulators/mupen64plus/mupen64plus.sh b/scriptmodules/emulators/mupen64plus/mupen64plus.sh
index a9f33fe690..ab7697da98 100755
--- a/scriptmodules/emulators/mupen64plus/mupen64plus.sh
+++ b/scriptmodules/emulators/mupen64plus/mupen64plus.sh
@@ -254,6 +254,10 @@ function testCompatibility() {
             iniSet "EnableFBEmulation" "True"
             # Set native resolution factor of 1
             iniSet "UseNativeResolutionFactor" "1"
+            # Force 3-point bilinear filtering & disable shader/key cache on Pi
+            # See: https://github.com/gonetz/GLideN64/issues/1665
+            iniSet "bilinearMode" "False"
+            iniSet "EnableShadersStorage" "False"
             for game in "${GLideN64NativeResolution_blacklist[@]}"; do
                 if [[ "${ROM,,}" == *"$game"* ]]; then
                     iniSet "UseNativeResolutionFactor" "0"
diff --git a/scriptmodules/emulators/mupen64plus/rpi-yuv.diff b/scriptmodules/emulators/mupen64plus/rpi-yuv.diff
new file mode 100644
index 0000000000..19430f00e1
--- /dev/null
+++ b/scriptmodules/emulators/mupen64plus/rpi-yuv.diff
@@ -0,0 +1,26 @@
+diff --git a/src/Graphics/OpenGLContext/GLSL/glsl_CombinerProgramBuilder.cpp b/src/Graphics/OpenGLContext/GLSL/glsl_CombinerProgramBuilder.cpp
+index ae8c2e7..9f61a39 100644
+--- a/GLideN64/src/Graphics/OpenGLContext/GLSL/glsl_CombinerProgramBuilder.cpp
++++ b/GLideN64/src/Graphics/OpenGLContext/GLSL/glsl_CombinerProgramBuilder.cpp
+@@ -1167,10 +1167,7 @@ public:
+ 			m_part =
+ 				"  nCurrentTile = 0; \n"
+ 				"  lowp vec4 readtex0;																\n"
+-				"  if (uBiLerp[0] != 0)																\n"
+ 				"    readtex0 = readTex(uTex0, vTexCoord0, uFbMonochrome[0], uFbFixedAlpha[0]);		\n"
+-				"  else																				\n"
+-				"    readtex0 = YUV_Convert(uTex0, vTexCoord0, uTextureConvert[0], uTextureFormat[0], readtex0);	\n"
+ 				;
+ 		} else {
+ 			if (config.video.multisampling > 0) {
+@@ -1205,10 +1202,7 @@ public:
+ 			m_part =
+ 				"  nCurrentTile = 1; \n"
+ 				"  lowp vec4 readtex1;																\n"
+-				"  if (uBiLerp[1] != 0)																\n"
+ 				"    readtex1 = readTex(uTex1, vTexCoord1, uFbMonochrome[1], uFbFixedAlpha[1]);		\n"
+-				"  else																				\n"
+-				"    readtex1 = YUV_Convert(uTex1, vTexCoord1, uTextureConvert[1], uTextureFormat[1], readtex0);	\n"
+ 				;
+ 		} else {
+ 			if (config.video.multisampling > 0) {