diff --git a/src/diff/props.js b/src/diff/props.js
index bbf0ed62b9..a756e71afc 100644
--- a/src/diff/props.js
+++ b/src/diff/props.js
@@ -78,6 +78,8 @@ export function setProperty(dom, name, value, oldValue, isSvg) {
 			// cast to `0` instead
 			name !== 'tabIndex' &&
 			name !== 'download' &&
+			name !== 'rowSpan' &&
+			name !== 'colSpan' &&
 			name in dom
 		) {
 			try {
diff --git a/test/browser/render.test.js b/test/browser/render.test.js
index 84fa64e9aa..6fcb0dc355 100644
--- a/test/browser/render.test.js
+++ b/test/browser/render.test.js
@@ -1244,4 +1244,46 @@ describe('render()', () => {
 		expect(items[0]).to.have.property('parentNode').that.should.exist;
 		expect(items[1]).to.have.property('parentNode').that.should.exist;
 	});
+
+	// Test for #3969
+	it('should clear rowspan and colspan', () => {
+		let update;
+		class App extends Component {
+			constructor(props) {
+				super(props);
+				this.state = { active: true };
+				update = this.setState.bind(this);
+			}
+
+			render() {
+				return (
+					<div>
+						{this.state.active ? (
+							<table>
+								<tr>
+									<td rowSpan={2} colSpan={2}>
+										Foo
+									</td>
+								</tr>
+							</table>
+						) : (
+							<table>
+								<tr>
+									<td>Foo</td>
+								</tr>
+							</table>
+						)}
+					</div>
+				);
+			}
+		}
+
+		render(<App />, scratch);
+
+		update({ active: false });
+		rerender();
+
+		expect(scratch.querySelector('td[rowspan]')).to.equal(null);
+		expect(scratch.querySelector('td[colspan]')).to.equal(null);
+	});
 });