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Citing GPCRdb

If you use GPCRdb in your work, please cite one or more of the following:

Main reference for GPCRdb

  • Pándy-Szekeres G, Munk C, Tsonkov TM, Mordalski S, Harpsøe K, Hauser AS, Bojarski AJ, Gloriam DE. GPCRdb in 2018: adding GPCR structure models and ligands. 2017, Nucleic Acids Res., Nov 16. 10.1093/nar/gkx1109

Introduction to new users (review)

  • Munk, C., Isberg, V., Mordalski, S., Harpsøe, K., Rataj, K., Hauser, A. S., Kolb, P., Bojarski, A. J., Vriend, G. , and Gloriam, D. E. GPCRdb: the G protein-coupled receptor database – an introduction. 2016, Br J Pharmacol, May 8. 10.1111/bph.13509

Structure-based alignments and generic residue numbering

  • V Isberg, C de Graaf, A Bortolato, V Cherezov, V Katritch, F Marshall, S Mordalski, J-P Pin, RC Stevens, G Vriend, DE Gloriam, "Generic GPCR Residue Numbers - Aligning Topology Maps While Minding The Gaps", 2015, Trends Pharmacol Sci, 36(1), 22–31. 10.1016/
  • R van der Kant, G Vriend, "Alpha-Bulges in G Protein-Coupled Receptors", 2014, Int J Mol Sci, 15(5), 7841-7864. 10.3390/ijms15057841

GPCR drugs and targets

  • Hauser, A. S., Misty, A, Mathias, R., Schiöth, H. B., Gloriam, D. E., "Trends in GPCR drug discovery: new agents, targets and indications", 2017, Nature Reviews Drug Discovery, in print, 10.1038/nrd.2017.178

GPCR-G protein selectivity

  • Flock, T., Hauser, A. S., Lund, N., Gloriam, D. E., Balaji, S., & Babu, M. M., "Selectivity determinants of GPCR–G-protein binding.", 2017, Nature, May 18;545(7654):317-322 10.1038/nature22070

Mutation design tool

  • C Munk, K Harpsøe, A Hauser, V Isberg, DE Gloriam, "Integrating structural and mutagenesis data to elucidate GPCR ligand binding", 2016, Curr Opin Pharcol, 30, 51–58. `10.1016/j.coph.2016.07.003`_

Crystal structure fragment-based pharmacophore models

  • K Fidom, V Isberg, A Hauser, S Mordalski, T Lehto, AJ Bojarski, DE Gloriam, "A New Crystal Structure Fragment-Based Pharmacophore Method for G Protein-Coupled Receptors", 2015, Methods, 71, 104–112. 10.1016/j.ymeth.2014.09.009

GPCR specific PDF reader

  • B Vroling, D Thorne, P McDermott, TK Attwood, G Vriend, S Pettifer, "Integrating GPCR-specific information with full text articles", 2011, BMC Bioinformatics, 12, 362. 10.1186/1471-2105-12-362

Older GPCRdb articles

  • V Isberg, S Mordalski, C Munk, K Rataj, K Harpsøe, AS Hauser, B Vroling, AJ Bojarski, G Vriend, DE Gloriam. "GPCRdb: an information system for G protein-coupled receptors", 2016, Nucleic Acids Res., 44, D356-D364. 10.1093/nar/gkv1178
  • V Isberg, B Vroling, R van der Kant, K Li, G Vriend* and DE Gloriam*, "GPCRDB: an information system for G protein-coupled receptors", 2014, Nucleic Acids Res., 42 (D1), D422-D425. 10.1093/nar/gkt1255
  • B Vroling, M Sanders, C Baakman, A Borrmann, S Verhoeven, J Klomp, L Oliveira, J de Vlieg, G Vriend, "GPCRDB: information system for G protein-coupled receptors", 2011, Nucleic Acids Res., 39(suppl 1), D309-19. 10.1093/nar/gkq1009
  • F Horn, E Bettler, L Oliveira, F Campagne, FE Cohen, G Vriend, "GPCRDB information system for G protein-coupled receptors", 2003, Nucleic Acids Res., 31(1), 294-297. 10.1093/nar/gkg103
  • F Horn, G Vriend, FE Cohen, "Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems", 2001, Nucleic Acids Res., 29(1), 346-349. 10.1093/nar/29.1.346
  • F Horn, J Weare, MW Beukers, S Hörsch, A Bairoch, W Chen, Ø Edvardsen, F Campagne, G Vriend, "GPCRDB: An information system for G protein-coupled receptors", 1998, Nucleic Acids Res., 26(1), 275-279. 10.1093/nar/26.1.275