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Welcome to GPCRdb's documentation

GPCRdb contains data, diagrams and web tools for G protein-coupled receptors (GPCRs). Users can browse all GPCR crystal structures and the largest collections of receptor mutants. Diagrams can be produced and downloaded to illustrate receptor residues (snake-plot and helix box diagrams) and relationships (phylogenetic trees). Reference (crystal) structure-based sequence alignments take into account helix bulges and constrictions, display statistics of amino acid conservation and have been assigned generic residue numbering for equivalent residues in different receptors

The source code and source data are freely available on GitHub.

The documentation in organized into four sections:

.. toctree::
    :maxdepth: 2
    :caption: Tutorial

    tutorial_receptors
    tutorial_structures
    tutorial_mutations
    tutorial_sites

.. toctree::
    :maxdepth: 2
    :caption: User documentation

    receptors
    signalproteins
    sequences
    structures
    constructs
    mutations
    sites
    generic_numbering
    drugs
    nhs
    variants

.. toctree::
    :maxdepth: 2
    :caption: Developer documentation

    web_services
    contributing
    local_installation
    coding_style
    git_workflow
    reload_database
    building_a_database

.. toctree::
    :maxdepth: 2
    :caption: About GPCRdb

    about
    contact
    contributors
    citing
    acknowledgements
    legal_notice
    meetings
    linking
    external_servers