Permalink
Switch branches/tags
Nothing to show
Find file Copy path
Fetching contributors…
Cannot retrieve contributors at this time
31 lines (20 sloc) 1.04 KB

Mutations

Mutation browser

This video demonstrates how use the mutation browser to search for and visualize mutations for a family of receptors.

  • It is possible to limit the search to a particular part of the sequence, e.g. TM6.
  • The mutations are listed in table format, and it is possible to filter and order interactions by the values in each column.
  • By moving the pointer to a ligand name or reference, more details can be shown.
  • Snake and Helix box plots highlighting the mutated residues can be downloaded. The mutated residues are colored on a green-yellow-red scale according to effect on ligand binding.
Your browser does not support the video tag.

Questions

  • Look up mutations for histamine receptors. How many are available for generic position 3x32?
  • Look up mutations for your favorite family of GPCRs. How many are available?