diff --git a/pulp_python/tests/functional/api/test_consume_content.py b/pulp_python/tests/functional/api/test_consume_content.py
index 9c153cd1..98ac094e 100644
--- a/pulp_python/tests/functional/api/test_consume_content.py
+++ b/pulp_python/tests/functional/api/test_consume_content.py
@@ -21,6 +21,7 @@ def test_pip_consume_content(
         "install",
         "--no-deps",
         "--no-cache-dir",
+        "--no-build-isolation",
         "--force-reinstall",
         "--trusted-host",
         urlsplit(distro.base_url).hostname,
diff --git a/pulp_python/tests/functional/api/test_domains.py b/pulp_python/tests/functional/api/test_domains.py
index d5db104c..1efcf134 100644
--- a/pulp_python/tests/functional/api/test_domains.py
+++ b/pulp_python/tests/functional/api/test_domains.py
@@ -277,6 +277,7 @@ def test_domain_pypi_apis(
             "pip",
             "install",
             "--no-deps",
+            "--no-build-isolation",
             "--trusted-host",
             urlsplit(distro.base_url).hostname,
             "-i",
diff --git a/pulp_python/tests/functional/constants.py b/pulp_python/tests/functional/constants.py
index 7214c1a0..231ae1bc 100644
--- a/pulp_python/tests/functional/constants.py
+++ b/pulp_python/tests/functional/constants.py
@@ -124,19 +124,22 @@
     "aiohttp",  # matches 7
     "bcrypt",  # matches 8
     "celery",  # matches 13
+    "crane",  # matches 0
     "Django",  # matches 31
+    "pulp-2to3-migration",  # matches 2
     "pytz",  # matches 6
     "scipy",  # matches 23
     "setuptools",  # matches 2
     "shelf-reader",  # matches 2
+    "twine",  # matches 14
 ]
-PYTHON_LG_PACKAGE_COUNT = 92
+PYTHON_LG_PACKAGE_COUNT = 108
 PYTHON_LG_FIXTURE_SUMMARY = {PYTHON_CONTENT_NAME: PYTHON_LG_PACKAGE_COUNT}
 PYTHON_LG_FIXTURE_COUNTS = {
-    "latest_3": 51,
-    "sdist": 28,
-    "bdist_wheel": 64,
-    "multi": 34,  # keep_latest=1, package_types="bdist_wheel", prereleases=False
+    "latest_3": 59,
+    "sdist": 36,
+    "bdist_wheel": 72,
+    "multi": 36,  # keep_latest=1, package_types="bdist_wheel", prereleases=False
 }
 
 DJANGO_LATEST_3 = 4  # latest version has 2 dists, each other has 1