diff --git a/docs/workflows/upload-publish.rst b/docs/workflows/upload-publish.rst
index e5884e76515..9b2aa580b5d 100644
--- a/docs/workflows/upload-publish.rst
+++ b/docs/workflows/upload-publish.rst
@@ -1,2 +1,35 @@
 Upload and Publish
 ==================
+
+Chunked Uploads
+---------------
+
+For large file uploads, Pulp supports uploading files in chunks. To begin uploading a file in
+chunks, an initial PUT request must be sent to the ``/pulp/api/v3/uploads`` endpoint::
+
+    http --form PUT :8000/pulp/api/v3/uploads/ file@./chunkaa 'Content-Range:bytes 0-6291455/32095676'
+
+This returns an upload href (e.g. ``/pulp/api/v3/uploads/a8b5a7f7-2f22-460d-ab20-d5616cb71cdd/``) that can
+be used for subsequent chunks::
+
+    http --form PUT :8000/pulp/api/v3/uploads/a8b5a7f7-2f22-460d-ab20-d5616cb71cdd/ file@./chunkbb 'Content-Range:bytes 6291456-10485759/32095676'
+
+Once all chunks have been uploaded, a final POST request with the file md5 can be sent to complete the
+upload::
+
+    http POST :8000/pulp/api/v3/uploads/a8b5a7f7-2f22-460d-ab20-d5616cb71cdd/ md5=037a47d93670e64f2b1038e6f90e4cfd
+
+Then the artifact may be created with the upload href::
+
+    http POST :8000/pulp/api/v3/artifacts/ upload=/pulp/api/v3/uploads/a8b5a7f7-2f22-460d-ab20-d5616cb71cdd/
+
+Note that after creating an artifact from an upload, the upload gets deleted and cannot be re-used.
+
+Putting this altogether, here is an example that uploads a 1.iso file in two chunks::
+
+   curl -O https://repos.fedorapeople.org/repos/pulp/pulp/fixtures/file-large/1.iso
+   split --bytes=6M 1.iso chunk
+   export UPLOAD=$(http --form PUT :8000/pulp/api/v3/uploads/ file@./chunkaa 'Content-Range:bytes 0-6291455/32095676'  | jq -r '._href')
+   http --form PUT :8000$UPLOAD file@./chunkab 'Content-Range:bytes 6291456-10485759/32095676'
+   http POST :8000$UPLOAD md5=037a47d93670e64f2b1038e6f90e4cfd
+   http POST :8000/pulp/api/v3/artifacts/ upload=$UPLOAD
diff --git a/pulpcore/app/files.py b/pulpcore/app/files.py
index 9e487e7b429..684f7597a1a 100644
--- a/pulpcore/app/files.py
+++ b/pulpcore/app/files.py
@@ -1,4 +1,5 @@
 import hashlib
+import os
 from django.core.files.uploadhandler import TemporaryFileUploadHandler
 from django.core.files.uploadedfile import TemporaryUploadedFile
 
@@ -14,6 +15,25 @@ def __init__(self, name, content_type, size, charset, content_type_extra=None):
             self.hashers[hasher] = getattr(hashlib, hasher)()
         super().__init__(name, content_type, size, charset, content_type_extra)
 
+    @classmethod
+    def from_file(cls, file):
+        """
+        Create a PulpTemporaryUploadedFile from a file system file
+
+        Args:
+            file (File): a filesystem file
+
+        Returns:
+            PulpTemporaryUploadedFile: instantiated instance from file
+        """
+        name = os.path.basename(file.name)
+        instance = cls(name, '', file.size, '', '')
+        instance.file = file
+        data = file.read()
+        for hasher in hashlib.algorithms_guaranteed:
+            instance.hashers[hasher].update(data)
+        return instance
+
 
 class HashingFileUploadHandler(TemporaryFileUploadHandler):
     """
diff --git a/pulpcore/app/migrations/0004_upload.py b/pulpcore/app/migrations/0004_upload.py
new file mode 100644
index 00000000000..c8f30b4cbd2
--- /dev/null
+++ b/pulpcore/app/migrations/0004_upload.py
@@ -0,0 +1,34 @@
+# Generated by Django 2.1.7 on 2019-02-28 11:57
+
+from django.conf import settings
+from django.db import migrations, models
+import django.db.models.deletion
+import drf_chunked_upload.models
+import uuid
+
+
+class Migration(migrations.Migration):
+
+    dependencies = [
+        migrations.swappable_dependency(settings.AUTH_USER_MODEL),
+        ('pulp_app', '0003_repositoryversioncontentdetails'),
+    ]
+
+    operations = [
+        migrations.CreateModel(
+            name='Upload',
+            fields=[
+                ('id', models.UUIDField(default=uuid.uuid4, editable=False, primary_key=True, serialize=False)),
+                ('file', models.FileField(max_length=255, null=True, upload_to=drf_chunked_upload.models.generate_filename)),
+                ('filename', models.CharField(max_length=255)),
+                ('offset', models.BigIntegerField(default=0)),
+                ('created_at', models.DateTimeField(auto_now_add=True)),
+                ('status', models.PositiveSmallIntegerField(choices=[(1, 'Incomplete'), (2, 'Complete')], default=1)),
+                ('completed_at', models.DateTimeField(blank=True, null=True)),
+                ('user', models.ForeignKey(editable=False, on_delete=django.db.models.deletion.CASCADE, related_name='upload', to=settings.AUTH_USER_MODEL)),
+            ],
+            options={
+                'abstract': False,
+            },
+        ),
+    ]
diff --git a/pulpcore/app/models/__init__.py b/pulpcore/app/models/__init__.py
index c74706c96bf..e43e3c966be 100644
--- a/pulpcore/app/models/__init__.py
+++ b/pulpcore/app/models/__init__.py
@@ -1,7 +1,7 @@
 # https://docs.djangoproject.com/en/dev/topics/db/models/#organizing-models-in-a-package
 
 from .base import Model, MasterModel  # noqa
-from .content import Artifact, Content, ContentArtifact, RemoteArtifact  # noqa
+from .content import Artifact, Content, ContentArtifact, RemoteArtifact, Upload  # noqa
 from .generic import GenericRelationModel  # noqa
 from .publication import (  # noqa
     ContentGuard,
diff --git a/pulpcore/app/models/content.py b/pulpcore/app/models/content.py
index 2b5a6018b19..99090399e56 100644
--- a/pulpcore/app/models/content.py
+++ b/pulpcore/app/models/content.py
@@ -6,6 +6,7 @@
 from django.core import validators
 from django.db import IntegrityError, models, transaction
 from django.forms.models import model_to_dict
+from drf_chunked_upload.models import ChunkedUpload
 
 from itertools import chain
 
@@ -340,3 +341,7 @@ class RemoteArtifact(Model, QueryMixin):
 
     class Meta:
         unique_together = ('content_artifact', 'remote')
+
+
+class Upload(ChunkedUpload):
+    pass
diff --git a/pulpcore/app/serializers/__init__.py b/pulpcore/app/serializers/__init__.py
index a8a923dcb23..8050716c236 100644
--- a/pulpcore/app/serializers/__init__.py
+++ b/pulpcore/app/serializers/__init__.py
@@ -25,6 +25,7 @@
     NoArtifactContentSerializer,
     SingleArtifactContentSerializer,
     MultipleArtifactContentSerializer,
+    UploadSerializer,
 )
 from .progress import ProgressReportSerializer  # noqa
 from .publication import (  # noqa
diff --git a/pulpcore/app/serializers/content.py b/pulpcore/app/serializers/content.py
index c37c1c3801c..cafe04b6211 100644
--- a/pulpcore/app/serializers/content.py
+++ b/pulpcore/app/serializers/content.py
@@ -2,10 +2,11 @@
 import hashlib
 
 from django.db import transaction
+from drf_chunked_upload.serializers import ChunkedUploadSerializer
 from rest_framework import serializers
 from rest_framework.validators import UniqueValidator
 
-from pulpcore.app import models
+from pulpcore.app import models, files
 from pulpcore.app.serializers import base, fields
 
 
@@ -98,7 +99,14 @@ class ArtifactSerializer(base.ModelSerializer):
 
     file = serializers.FileField(
         help_text=_("The stored file."),
-        required=True
+        required=False
+    )
+
+    upload = serializers.HyperlinkedRelatedField(
+        view_name="upload-detail",
+        write_only=True,
+        required=False,
+        queryset=models.Upload.objects.filter(status=models.Upload.COMPLETE)
     )
 
     size = serializers.IntegerField(
@@ -156,6 +164,15 @@ def validate(self, data):
         """
         super().validate(data)
 
+        if ('file' not in data and 'upload' not in data) or \
+                ('file' in data and 'upload' in data):
+            raise serializers.ValidationError(_("Either 'file' or 'upload' parameter must be "
+                                                "supplied but not both."))
+
+        if 'upload' in data:
+            self.upload = data.pop('upload')
+            data['file'] = files.PulpTemporaryUploadedFile.from_file(self.upload.file.file)
+
         if 'size' in data:
             if data['file'].size != int(data['size']):
                 raise serializers.ValidationError(_("The size did not match actual size of file."))
@@ -180,7 +197,36 @@ def validate(self, data):
                     validator(digest)
         return data
 
+    def create(self, validated_data):
+        """
+        Create the artifact and delete its associated upload (if there is one)
+
+        Args:
+            validated_data (dict): Data to save to the database
+        """
+        artifact = super().create(validated_data)
+        # creating an artifact will move the upload file so we need to delete the db record
+        self.upload.delete()
+        return artifact
+
     class Meta:
         model = models.Artifact
         fields = base.ModelSerializer.Meta.fields + ('file', 'size', 'md5', 'sha1', 'sha224',
-                                                     'sha256', 'sha384', 'sha512')
+                                                     'sha256', 'sha384', 'sha512', 'upload')
+
+
+class UploadSerializer(base.ModelSerializer):
+    """Serializer for chunked uploads."""
+    viewname = 'uploads:upload-detail'
+
+    _href = base.IdentityField(
+        view_name='upload-detail',
+    )
+
+    file = serializers.FileField(
+        write_only=True,
+    )
+
+    class Meta(ChunkedUploadSerializer.Meta):
+        model = models.Upload
+        fields = ('_href', 'file', 'offset', 'expires_at')
diff --git a/pulpcore/app/settings.py b/pulpcore/app/settings.py
index 9a59f31f4c0..8e43d6d36d3 100644
--- a/pulpcore/app/settings.py
+++ b/pulpcore/app/settings.py
@@ -63,6 +63,7 @@
     'django_filters',
     'drf_yasg',
     'rest_framework',
+    'drf_chunked_upload',
     # pulp core app
     'pulpcore.app',
 ]
diff --git a/pulpcore/app/urls.py b/pulpcore/app/urls.py
index ebb90e3841c..01aaf51a055 100644
--- a/pulpcore/app/urls.py
+++ b/pulpcore/app/urls.py
@@ -8,7 +8,7 @@
 
 from pulpcore.app.apps import pulp_plugin_configs
 from pulpcore.app.openapigenerator import PulpOpenAPISchemaGenerator
-from pulpcore.app.views import OrphansView, StatusView
+from pulpcore.app.views import OrphansView, StatusView, UploadView
 from pulpcore.constants import API_ROOT
 
 import logging
@@ -144,6 +144,16 @@ def __repr__(self):
     name='schema-redoc')
 )
 
+urlpatterns.append(url(
+    r'^{api_root}uploads/(?P<pk>.*)/$'.format(api_root=API_ROOT),
+    UploadView.as_view(),
+    name='upload-detail')
+)
+urlpatterns.append(url(
+    r'^{api_root}uploads/$'.format(api_root=API_ROOT),
+    UploadView.as_view())
+)
+
 schema_view = get_schema_view(
     title='Pulp API',
     permission_classes=[permissions.AllowAny],
diff --git a/pulpcore/app/views/__init__.py b/pulpcore/app/views/__init__.py
index 86eedea5126..1487b884088 100644
--- a/pulpcore/app/views/__init__.py
+++ b/pulpcore/app/views/__init__.py
@@ -1,2 +1,3 @@
 from .orphans import OrphansView  # noqa
 from .status import StatusView  # noqa
+from .upload import UploadView  # noqa
diff --git a/pulpcore/app/views/upload.py b/pulpcore/app/views/upload.py
new file mode 100644
index 00000000000..eee713522ae
--- /dev/null
+++ b/pulpcore/app/views/upload.py
@@ -0,0 +1,10 @@
+from drf_chunked_upload.views import ChunkedUploadView
+from pulpcore.app.models import Upload
+from pulpcore.app.serializers import UploadSerializer
+
+
+class UploadView(ChunkedUploadView):
+    """View for chunked uploads."""
+    model = Upload
+    serializer_class = UploadSerializer
+    queryset = Upload.objects.all()
diff --git a/pulpcore/app/viewsets/content.py b/pulpcore/app/viewsets/content.py
index 50e2f74e53a..7c376c91f3a 100644
--- a/pulpcore/app/viewsets/content.py
+++ b/pulpcore/app/viewsets/content.py
@@ -2,7 +2,7 @@
 
 from django.db import models
 from rest_framework import status, mixins
-from rest_framework.parsers import MultiPartParser, FormParser
+from rest_framework.parsers import FormParser, JSONParser, MultiPartParser
 from rest_framework.response import Response
 
 from pulpcore.app.models import Artifact, Content
@@ -39,7 +39,7 @@ class ArtifactViewSet(NamedModelViewSet,
     queryset = Artifact.objects.all()
     serializer_class = ArtifactSerializer
     filterset_class = ArtifactFilter
-    parser_classes = (MultiPartParser, FormParser)
+    parser_classes = (MultiPartParser, FormParser, JSONParser)
 
     def destroy(self, request, pk):
         """
diff --git a/setup.py b/setup.py
index 7aa821f100d..653cf39fa66 100755
--- a/setup.py
+++ b/setup.py
@@ -18,7 +18,8 @@
     'redis<3.2.0',
     'setuptools',
     'dynaconf>=1.0.4',
-    'whitenoise'
+    'whitenoise',
+    'drf-chunked-upload'
 ]
 
 setup(