diff --git a/PyInstaller/depend/utils.py b/PyInstaller/depend/utils.py
index b1e1b2a873..04e4736012 100644
--- a/PyInstaller/depend/utils.py
+++ b/PyInstaller/depend/utils.py
@@ -306,7 +306,13 @@ def _restorePaths(old):
     # local paths to library search paths, then replaces original values.
     old = _setPaths()
     for cbin in cbinaries:
-        cpath = find_library(os.path.splitext(cbin)[0])
+        try:
+            # There is an issue with find_library() where it can run into
+            # errors trying to locate the library. See #5734.
+            cpath = find_library(os.path.splitext(cbin)[0])
+        except FileNotFoundError:
+            # In these cases, find_library() should return None.
+            cpath = None
         if is_unix:
             # CAVEAT: find_library() is not the correct function. Ctype's
             # documentation says that it is meant to resolve only the filename
diff --git a/news/5734.bugfix.rst b/news/5734.bugfix.rst
new file mode 100644
index 0000000000..9a784eac03
--- /dev/null
+++ b/news/5734.bugfix.rst
@@ -0,0 +1,2 @@
+Fix a build error triggered by scanning ``ctypes.CDLL('libc.so')`` on certain
+Linux C compiler combinations.
diff --git a/tests/functional/test_regression.py b/tests/functional/test_regression.py
index 7c0dc6f257..b15cab8ac3 100644
--- a/tests/functional/test_regression.py
+++ b/tests/functional/test_regression.py
@@ -92,3 +92,13 @@ def test_issue_4141(pyi_builder):  #script_dir,
     pyi_builder.test_script('pyi_issue_4141.py',
                             app_name="main", run_from_path=True,
                             pyi_args=['--path', str(extra_path)])
+
+
+def test_5734():
+    """
+    In a regression this will raise a:
+        FileNotFoundError: [Errno 2] No such file or directory: b'liblibc.a'
+    on some Linux/gcc combinations.
+    """
+    from PyInstaller.depend.utils import _resolveCtypesImports
+    _resolveCtypesImports(["libc"])