diff --git a/ChangeLog b/ChangeLog
index e38a3b651..7c8a7d443 100644
--- a/ChangeLog
+++ b/ChangeLog
@@ -12,7 +12,9 @@ What's New in astroid 2.12.10?
 ==============================
 Release date: TBA
 
+* ``decorators.cached`` now gets its cache cleared by calling ``AstroidManager.clear_cache``.
 
+  Refs #1780
 
 What's New in astroid 2.12.9?
 =============================
diff --git a/astroid/_cache.py b/astroid/_cache.py
new file mode 100644
index 000000000..fc4ddc205
--- /dev/null
+++ b/astroid/_cache.py
@@ -0,0 +1,26 @@
+# Licensed under the LGPL: https://www.gnu.org/licenses/old-licenses/lgpl-2.1.en.html
+# For details: https://github.com/PyCQA/astroid/blob/main/LICENSE
+# Copyright (c) https://github.com/PyCQA/astroid/blob/main/CONTRIBUTORS.txt
+
+from __future__ import annotations
+
+from typing import Any
+
+
+class CacheManager:
+    """Manager of caches, to be used as a singleton."""
+
+    def __init__(self) -> None:
+        self.dict_caches: list[dict[Any, Any]] = []
+
+    def clear_all_caches(self) -> None:
+        """Clear all caches."""
+        for dict_cache in self.dict_caches:
+            dict_cache.clear()
+
+    def add_dict_cache(self, cache: dict[Any, Any]) -> None:
+        """Add a dictionary cache to the manager."""
+        self.dict_caches.append(cache)
+
+
+CACHE_MANAGER = CacheManager()
diff --git a/astroid/decorators.py b/astroid/decorators.py
index c4f44dcd2..e9cc3292c 100644
--- a/astroid/decorators.py
+++ b/astroid/decorators.py
@@ -15,7 +15,7 @@
 
 import wrapt
 
-from astroid import util
+from astroid import _cache, util
 from astroid.context import InferenceContext
 from astroid.exceptions import InferenceError
 
@@ -34,6 +34,7 @@ def cached(func, instance, args, kwargs):
     cache = getattr(instance, "__cache", None)
     if cache is None:
         instance.__cache = cache = {}
+        _cache.CACHE_MANAGER.add_dict_cache(cache)
     try:
         return cache[func]
     except KeyError:
diff --git a/astroid/manager.py b/astroid/manager.py
index 25373a6b4..ff472256f 100644
--- a/astroid/manager.py
+++ b/astroid/manager.py
@@ -16,6 +16,7 @@
 from importlib.util import find_spec, module_from_spec
 from typing import TYPE_CHECKING, ClassVar
 
+from astroid._cache import CACHE_MANAGER
 from astroid.const import BRAIN_MODULES_DIRECTORY
 from astroid.exceptions import AstroidBuildingError, AstroidImportError
 from astroid.interpreter._import import spec, util
@@ -382,6 +383,8 @@ def clear_cache(self) -> None:
         # NB: not a new TransformVisitor()
         AstroidManager.brain["_transform"].transforms = collections.defaultdict(list)
 
+        CACHE_MANAGER.clear_all_caches()
+
         for lru_cache in (
             LookupMixIn.lookup,
             _cache_normalize_path_,