diff --git a/rope/refactor/patchedast.py b/rope/refactor/patchedast.py
index 5a8c59dd7..d8ed4e063 100644
--- a/rope/refactor/patchedast.py
+++ b/rope/refactor/patchedast.py
@@ -97,6 +97,15 @@ def __call__(self, node):
             node.sorted_children = ast.get_children(node)
 
     def _handle(self, node, base_children, eat_parens=False, eat_spaces=False):
+        if hasattr(node, "region"):
+            # ???: The same node was seen twice; what should we do?
+            warnings.warn(
+                "Node <%s> has been already patched; please report!"
+                % node.__class__.__name__,
+                RuntimeWarning,
+            )
+            return
+
         base_children = collections.deque(base_children)
         self.children_stack.append(base_children)
         children = collections.deque()