diff --git a/Lib/test/libregrtest/utils.py b/Lib/test/libregrtest/utils.py
index 7765ae8a933be4..837f73b28b4018 100644
--- a/Lib/test/libregrtest/utils.py
+++ b/Lib/test/libregrtest/utils.py
@@ -276,6 +276,15 @@ def clear_caches():
         pass
     else:
         inspect._shadowed_dict_from_mro_tuple.cache_clear()
+        inspect._filesbymodname.clear()
+        inspect.modulesbyfile.clear()
+
+    try:
+        importlib_metadata = sys.modules['importlib.metadata']
+    except KeyError:
+        pass
+    else:
+        importlib_metadata.FastPath.__new__.cache_clear()
 
 
 def get_build_info():