diff --git a/Include/internal/pycore_stats.h b/Include/internal/pycore_stats.h
index ab649574f33dbf..24f239a2135b93 100644
--- a/Include/internal/pycore_stats.h
+++ b/Include/internal/pycore_stats.h
@@ -77,7 +77,7 @@ PyAPI_FUNC(PyObject*) _Py_GetSpecializationStats(void);
 #define RARE_EVENT_INTERP_INC(interp, name) \
     do { \
         /* saturating add */ \
-        int val = FT_ATOMIC_LOAD_UINT8_RELAXED(interp->rare_events.name); \
+        uint8_t val = FT_ATOMIC_LOAD_UINT8_RELAXED(interp->rare_events.name); \
         if (val < UINT8_MAX) { \
             FT_ATOMIC_STORE_UINT8(interp->rare_events.name, val + 1); \
         } \
diff --git a/Lib/test/test_generated_cases.py b/Lib/test/test_generated_cases.py
index ec44a0f9ce3fb3..6e0e2eafd3281c 100644
--- a/Lib/test/test_generated_cases.py
+++ b/Lib/test/test_generated_cases.py
@@ -1572,7 +1572,7 @@ def test_instruction_size_macro(self):
             frame->instr_ptr = next_instr;
             next_instr += 1;
             INSTRUCTION_STATS(OP);
-            frame->return_offset = 1 ;
+            frame->return_offset = 1u ;
             DISPATCH();
         }
         """
diff --git a/Modules/_sre/sre.c b/Modules/_sre/sre.c
index 49eb52b635bfbb..fdf00e6499cb6b 100644
--- a/Modules/_sre/sre.c
+++ b/Modules/_sre/sre.c
@@ -2359,7 +2359,7 @@ match_getindex(MatchObject* self, PyObject* index)
     }
 
     // Check that i*2 cannot overflow to make static analyzers happy
-    assert(i <= SRE_MAXGROUPS);
+    assert((size_t)i <= SRE_MAXGROUPS);
     return i;
 }
 
diff --git a/Python/executor_cases.c.h b/Python/executor_cases.c.h
index 3dcb2decc43737..635ca659394c32 100644
--- a/Python/executor_cases.c.h
+++ b/Python/executor_cases.c.h
@@ -1688,7 +1688,7 @@
             _PyInterpreterFrame* pushed_frame = _PyFrame_PushUnchecked(tstate, getitem, 2, frame);
             pushed_frame->localsplus[0] = container;
             pushed_frame->localsplus[1] = sub;
-            frame->return_offset = 6 ;
+            frame->return_offset = 6u ;
             new_frame = PyStackRef_Wrap(pushed_frame);
             stack_pointer[-3] = new_frame;
             stack_pointer += -2;
@@ -2057,8 +2057,8 @@
             gen->gi_frame_state = FRAME_EXECUTING;
             gen->gi_exc_state.previous_item = tstate->exc_info;
             tstate->exc_info = &gen->gi_exc_state;
-            assert( 2 + oparg <= UINT16_MAX);
-            frame->return_offset = (uint16_t)( 2 + oparg);
+            assert( 2u + oparg <= UINT16_MAX);
+            frame->return_offset = (uint16_t)( 2u + oparg);
             pushed_frame->previous = frame;
             gen_frame = PyStackRef_Wrap(pushed_frame);
             stack_pointer[-1] = gen_frame;
@@ -4610,7 +4610,7 @@
             gen->gi_exc_state.previous_item = tstate->exc_info;
             tstate->exc_info = &gen->gi_exc_state;
             pushed_frame->previous = frame;
-            frame->return_offset = (uint16_t)( 2 + oparg);
+            frame->return_offset = (uint16_t)( 2u + oparg);
             gen_frame = PyStackRef_Wrap(pushed_frame);
             stack_pointer[0] = gen_frame;
             stack_pointer += 1;
diff --git a/Python/generated_cases.c.h b/Python/generated_cases.c.h
index 7547eaad125370..c3e37f080fa6e4 100644
--- a/Python/generated_cases.c.h
+++ b/Python/generated_cases.c.h
@@ -653,7 +653,7 @@
                 _PyInterpreterFrame* pushed_frame = _PyFrame_PushUnchecked(tstate, getitem, 2, frame);
                 pushed_frame->localsplus[0] = container;
                 pushed_frame->localsplus[1] = sub;
-                frame->return_offset = 6 ;
+                frame->return_offset = 6u ;
                 new_frame = PyStackRef_Wrap(pushed_frame);
             }
             // _PUSH_FRAME
@@ -1587,7 +1587,7 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    frame->return_offset = 4 ;
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -2603,7 +2603,7 @@
                         if (new_frame == NULL) {
                             JUMP_TO_LABEL(error);
                         }
-                        assert( 1 == 1);
+                        assert( 1u == 1);
                         frame->return_offset = 1;
                         DISPATCH_INLINED(new_frame);
                     }
@@ -2883,8 +2883,8 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    assert( 4 == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
-                    frame->return_offset = 4 ;
+                    assert( 4u == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -5716,7 +5716,7 @@
                 gen->gi_exc_state.previous_item = tstate->exc_info;
                 tstate->exc_info = &gen->gi_exc_state;
                 pushed_frame->previous = frame;
-                frame->return_offset = (uint16_t)( 2 + oparg);
+                frame->return_offset = (uint16_t)( 2u + oparg);
                 gen_frame = PyStackRef_Wrap(pushed_frame);
             }
             // _PUSH_FRAME
@@ -6334,7 +6334,7 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    frame->return_offset = 4 ;
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -6547,7 +6547,7 @@
                         if (new_frame == NULL) {
                             JUMP_TO_LABEL(error);
                         }
-                        assert( 1 == 1);
+                        assert( 1u == 1);
                         frame->return_offset = 1;
                         DISPATCH_INLINED(new_frame);
                     }
@@ -6690,8 +6690,8 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    assert( 4 == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
-                    frame->return_offset = 4 ;
+                    assert( 4u == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -8060,7 +8060,7 @@
             stack_pointer += -1;
             assert(WITHIN_STACK_BOUNDS());
             new_frame->localsplus[1] = PyStackRef_FromPyObjectNew(name);
-            frame->return_offset = 10 ;
+            frame->return_offset = 10u ;
             DISPATCH_INLINED(new_frame);
         }
 
@@ -10459,8 +10459,8 @@
                     gen->gi_frame_state = FRAME_EXECUTING;
                     gen->gi_exc_state.previous_item = tstate->exc_info;
                     tstate->exc_info = &gen->gi_exc_state;
-                    assert( 2 + oparg <= UINT16_MAX);
-                    frame->return_offset = (uint16_t)( 2 + oparg);
+                    assert( 2u + oparg <= UINT16_MAX);
+                    frame->return_offset = (uint16_t)( 2u + oparg);
                     assert(gen_frame->previous == NULL);
                     gen_frame->previous = frame;
                     DISPATCH_INLINED(gen_frame);
@@ -10560,8 +10560,8 @@
                 gen->gi_frame_state = FRAME_EXECUTING;
                 gen->gi_exc_state.previous_item = tstate->exc_info;
                 tstate->exc_info = &gen->gi_exc_state;
-                assert( 2 + oparg <= UINT16_MAX);
-                frame->return_offset = (uint16_t)( 2 + oparg);
+                assert( 2u + oparg <= UINT16_MAX);
+                frame->return_offset = (uint16_t)( 2u + oparg);
                 pushed_frame->previous = frame;
                 gen_frame = PyStackRef_Wrap(pushed_frame);
             }
diff --git a/Tools/cases_generator/generators_common.py b/Tools/cases_generator/generators_common.py
index cc0edcdf6006fd..61e855eb003706 100644
--- a/Tools/cases_generator/generators_common.py
+++ b/Tools/cases_generator/generators_common.py
@@ -470,7 +470,7 @@ def instruction_size(self,
         """Replace the INSTRUCTION_SIZE macro with the size of the current instruction."""
         if uop.instruction_size is None:
             raise analysis_error("The INSTRUCTION_SIZE macro requires uop.instruction_size to be set", tkn)
-        self.out.emit(f" {uop.instruction_size} ")
+        self.out.emit(f" {uop.instruction_size}u ")
         return True
 
     def _print_storage(self, reason:str, storage: Storage) -> None: