diff --git a/Lib/test/test_ctypes/test_dlerror.py b/Lib/test/test_ctypes/test_dlerror.py
index 8af34e62b94faa..5658234f9ec66b 100644
--- a/Lib/test/test_ctypes/test_dlerror.py
+++ b/Lib/test/test_ctypes/test_dlerror.py
@@ -32,6 +32,7 @@
 
 @unittest.skipUnless(sys.platform.startswith('linux'),
                      'test requires GNU IFUNC support')
+@unittest.skipIf(test.support.linked_to_musl(), "Requires glibc")
 class TestNullDlsym(unittest.TestCase):
     """GH-126554: Ensure that we catch NULL dlsym return values