diff --git a/.github/CODEOWNERS b/.github/CODEOWNERS
index b190d8ac1ee955..91eb0b718d3cc0 100644
--- a/.github/CODEOWNERS
+++ b/.github/CODEOWNERS
@@ -27,6 +27,7 @@ Modules/Setup*                @erlend-aasland
 **/*genobject*                @markshannon
 **/*hamt*                     @1st1
 **/*jit*                      @brandtbucher @savannahostrowski
+Python/perf_jit_trampoline.c  # Exclude the owners of "**/*jit*", above.
 Objects/set*                  @rhettinger
 Objects/dict*                 @methane @markshannon
 Objects/typevarobject.c       @JelleZijlstra