diff --git a/backends/qualcomm/quantizer/utils.py b/backends/qualcomm/quantizer/utils.py
index ed9afd70ce6..c54b2bc3ebb 100644
--- a/backends/qualcomm/quantizer/utils.py
+++ b/backends/qualcomm/quantizer/utils.py
@@ -1055,17 +1055,25 @@ def annotate_layer_norm(node: Node, quantization_config: QuantizationConfig) ->
 
     if _is_annotated([node]):
         return
+    input_act_qspec = quantization_config.input_activation
 
     _annotate_input_qspec_map(
         node,
         act_node,
-        quantization_config.input_activation,
-    )
-    _annotate_input_qspec_map(
-        node,
-        weight_node,
-        quantization_config.input_activation,
+        input_act_qspec,
     )
+    if input_act_qspec.dtype == torch.int32:
+        _annotate_input_qspec_map(
+            node,
+            weight_node,
+            get_default_16bit_qnn_ptq_config().weight,
+        )
+    else:
+        _annotate_input_qspec_map(
+            node,
+            weight_node,
+            input_act_qspec,
+        )
     nodes_to_mark_annotated = [node, weight_node]
     if bias_node:
         _annotate_input_qspec_map(
diff --git a/backends/qualcomm/tests/test_qnn_delegate.py b/backends/qualcomm/tests/test_qnn_delegate.py
index 8abed68c630..f9fc2ea12e1 100644
--- a/backends/qualcomm/tests/test_qnn_delegate.py
+++ b/backends/qualcomm/tests/test_qnn_delegate.py
@@ -634,6 +634,16 @@ def test_qnn_backend_16a4w_conv2d(self):
                 )
                 self.lower_module_and_test_output(module, sample_input)
 
+    def test_qnn_backend_16a4w_layer_norm(self):
+        module = LayerNorm()  # noqa: F405
+        sample_input = (torch.randn(196, 768),)
+        module = self.get_qdq_module(
+            module,
+            sample_input,
+            quant_dtype=QuantDtype.use_16a4w,
+        )
+        self.lower_module_and_test_output(module, sample_input)
+
     def test_qnn_backend_16a4w_linear(self):
         module = Linear()  # noqa: F405
         sample_input = (torch.randn([3, 4]),)